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Items: 3

1.

miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS

(Submitter supplied) microRNAs (miRNAs) have been implicated in oligodendrogenesis and demyelinating diseases; however, identification of individual miRNAs responsible has remained elusive. Through targeted mutagenesis, we find that miR-219 is required for proper oligodendrocyte differentiation and myelination in vivo. Deletion of miR-338 together with miR-219 further exacerbates hypomyelination phenotypes. Temporally specific ablation reveals a critical role for miR-219 in oligodendrocyte remyelination after demyelination, while overexpression of miR-219 promotes precocious oligodendrocyte maturation and myelin regeneration. more...
Organism:
Mus musculus; Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL14844
14 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE80439
ID:
200080439

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Rattus norvegicus)

Organism:
Rattus norvegicus
333 Series
6659 Samples
Download data
Platform
Accession:
GPL14844
ID:
100014844

3.

OPC_Ctrl_1_genes

Organism:
Rattus norvegicus
Source name:
Oligodendrocyte, control
Platform:
GPL14844
Series:
GSE80439
Download data: FPKM_TRACKING
Sample
Accession:
GSM2127372
ID:
302127372

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db=gds|term=GSM2127372[Accession]|query=1|qty=3|blobid=MCID_674f98ad68e51b28f5845642|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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