GEO DataSets

(Submitter supplied) Oxidative stress is a common factor threating genomic stability in almost all aerobic organisms. Using a yeast screening system, we measured the frequency of mitotic recombination was greatly elevated after H2O2 treatment. H2O2 was able to break chromatid directly in G1 synchronized cells and homologous recombination was induced to repair DNA double stand breaks at S/G2 phase. By whole genome SNP microarray and sequencing, the patterns of H2O2 induced loss of heterozygosity (LOH; gene conversion and crossover), chromosomal rearrangement, and aneuploidy changes were revealed. more...

Organism:

Saccharomyces cerevisiae

Type:

Genome variation profiling by SNP array

Platforms:

GPL21552 GPL20144 GPL21553

169 Samples

Download data: GPR

(Submitter supplied) see manufacturer's web site at http://www.agilent.com/

Organism:

Saccharomyces cerevisiae

8 Series

1 Related Platform

390 Samples

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