GSM3557824[Accession] - GEO DataSets

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Items: 3

Select item 2001248781.

Peritoneal macrophage heterogeneity in decompensated liver cirrhosis

(Submitter supplied) Peritoneal macrophages (PM) are thought to regulate peritoneal inflammation and control bacterial infections in decompensated liver cirrhosis. The aim of this study was to characterize human PM heterogeneity. Employing CD206 surface expression, we identified subsets of human large (LPM) and small (SPM) PM, which differed in granularity and maturation states. FACS-sorted LPM from patients with decompensated cirrhosis revealed discrete transcriptome clusters, comprising more than 4000 differentially regulated genes involved in cell cycle, metabolism, and immune signaling.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL24324
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE124878

ID:: 200124878

Select item 1000243242.

[Clariom_S_Human_HT] Affymetrix Clariom S Assay HT, Human (Includes Pico Assay)

(Submitter supplied) This platform supports submissions for: Clariom S Assay HT: https://www.thermofisher.com/order/catalog/product/902969 Clariom S Pico Assay HT: https://www.thermofisher.com/order/catalog/product/902964 Annotations: #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg38 #%genome-version-ucsc=hg38 #%genome-version-ncbi=GRCh38 #%genome-version-create_date=2013-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg38 #%genome-lifted_from-version-ncbi=GRCh38 #%netaffx-annotation-date=2016-06-03 #%netaffx-annotation-netaffx-build=36 Protocol: See manufacturers website