GEO DataSets

(Submitter supplied) Hypochlorous acid (HOCl) is a potent oxidant that is produced endogenously in mammalian tissue by phagocytes. Exogenous exposure to HOCl also can occur following inhalation of chlorine gas. HOCl has been implicated as a source of oxidative stress associated atherosclerosis and other diseases. The purpose of this study was to identify dose-dependent transitions in cellular response to hypochlorous acid (HOCl), with a focus on understanding how various cellular defense and stress dose-responses overlap.

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3670

Platform:

GPL1261

25 Samples

Download data: CEL

Analysis of macrophage RAW 264.7 cells treated with up to 3.5 mM hypochlorous acid (HOCl). HOCl exposure can occur from chlorine gas inhalation or from endogenous sources of HOCl, such as respiratory burst by phagocytes. Results provide insight into the dose-dependent molecular response to HOCl.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 8 dose sets

Platform:

GPL1261

Series:

GSE15457

25 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4547 Series

40 Related Platforms

58950 Samples

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