GSM461962[Accession] - GEO DataSets

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Items: 4

Select item 2000185631.

Glucose Shortens the Lifespan of Caenorhabditis elegans by Down-Regulating Aquaporin Gene Expression

(Submitter supplied) Many studies have addressed the effect of dietary glycemic index on obesity and diabetes, but little is known about its effect on lifespan itself. We found that adding a small amount of glucose to the medium (0.1-2%) shortened the lifespan of C. elegans. Glucose shortened lifespan by inhibiting the activities of lifespan-extending transcription factors that are also inhibited by insulin signaling: the FOXO family member DAF-16 and the heat shock factor HSF-1. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL9450
14 Samples

Download data: GPR

Series

Accession:: GSE18563

ID:: 200018563

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000185612.

Adult C. elegans: Control daf-2 mutants treated with daf-16 RNAi vs. daf-2 mutants treated with empty vector RNAi

(Submitter supplied) Transcriptional profiling of adult C. elegans comparing daf-16(-); daf-2(-) animals with adult daf-2(-) animals.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL9450
8 Samples

Download data: GPR

Series

Accession:: GSE18561

ID:: 200018561

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000094503.

UCSF C. elegans 20K oligo array version 1

(Submitter supplied) We used oligonucleotide sets for C. elegans. We printed these oligonucleotides at high density on polylysine-coated glass slides, closely adhering to protocols available at http://microarrays.org.