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Items: 3

1.

Identification of LncRNA TRAF3IP2-AS1 as a key regulator of IL-17 signaling through the SRSF10-IRF1-Act1 axis in autoimmune diseases

(Submitter supplied) Our study indicates that lncRNA TRAF3IP2-AS1 serving as a negative regulator of Act1 transcriptional expression and IL-17 signaling pathway activity,recruits SRSF10 to downregulate the transcription of IRF1, which is itself a transcriptional factor for Act1. And the psoriasis-susceptible variant A4165G of TRAF3IP2-AS1 is a gain-of-function mutant that binds more strongly than the wild-type form to SRSF10. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29480
6 Samples
Download data: TXT
Series
Accession:
GSE165781
ID:
200165781
2.

DNBSEQ-T7 (Homo sapiens)

Platform
Accession:
GPL29480
ID:
100029480
3.

Hela cells, SRSF10-overexpression, rep2

Organism:
Homo sapiens
Source name:
Hela cells
Platform:
GPL29480
Series:
GSE165781
Download data: TXT
Sample
Accession:
GSM5049810
ID:
305049810
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db=gds|term=GSM5049810[Accession]|query=1|qty=2|blobid=MCID_674f9b822ced8a147a2a6ee8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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