GSM531770[Accession] - GEO DataSets

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Items: 4

Select item 2000212661.

Effect of Ursodeoxycholic acid on gene expression in the intestial epithelium

(Submitter supplied) Background & Aims: Ursodeoxycholic acid (UDCA) attenuates chemical and colitis-induced colon carcinogenesis in animal models. We investigated its mechanism of action on normal intestinal cells, in which carcinogenesis- or inflammation-related alterations do not interfere with the result. Methods: Alterations of gene expression were identified in Affymetrix arrays in isolated colon epithelium of mice fed with a diet containing 0.4% UDCA and were confirmed in the normal rat intestinal cell line IEC-6 by RT-PCR. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4372
Platform:: GPL8321
6 Samples

Download data: CEL, TXT

Series

Accession:: GSE21266

ID:: 200021266

Select item 43722.

Intestinal epithelium response to ursodeoxycholic acid

Analysis of normal colon epithelium of C57BL/6J females fed a standard diet containing 0.4% ursodeoxycholic acid (UDCA). UDCA mitigates colon carcinogenesis in humans and in animal models. Results provide insight into the molecular mechanisms underlying the anticarcinogenic action of UDCA.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 growth protocol sets

Platform:: GPL8321
Series:: GSE21266
6 Samples

Download data: CEL

DataSet

Accession:: GDS4372

ID:: 4372

Select item 1000083213.

[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...