GEO DataSets

(Submitter supplied) We employed a hybrid method based on Oxford Nanopore long-read sequencing and Illumina sequencing to characterize the AS landscapes, and to identify AS-derived neoantigens. Furthermore, we used the AlphaFold2 algorithm to analyze the structure of these putative neoantigens, thus offering structural insights for further drug development. These results lay the foundation for the development of therapies targeting UM-specific, AS-derived neoantigens.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL26167 GPL24676

38 Samples

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