GSM7119075[Accession] - GEO DataSets

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Items: 4

Select item 2002283431.

Histone lactylation couples cellular metabolism with the activation of developmental gene regulatory networks

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Gallus gallus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL19787 GPL26853
25 Samples

Download data: BEDGRAPH, BW, TXT

Series

Accession:: GSE228343

ID:: 200228343

PubMed Full text in PMC Similar studies

Select item 2002283352.

Histone lactylation couples cellular metabolism with the activation of developmental gene regulatory networks [NCC CUT&RUN]

(Submitter supplied) Embryonic cells engage in diverse types of metabolism to execute specialized tasks in the developing embryo. Recent studies have demonstrated that metabolic reprogramming can also drive changes in cell identity and behavior by affecting the expression of developmental genes. However, the connection between cellular metabolism and differential gene expression is still not well understood. Here we report found that histone lactylation, an epigenetic mark derived from glycolysis-derived lactate, couples the metabolic state of embryonic cells with gene expression and the activation of gene regulatory networks. more...