GSM744690[Accession] - GEO DataSets

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Items: 3

Select item 2000300901.

A promoter DNA demethylation landscape of human hematopoietic differentiation

(Submitter supplied) Global mechanisms defining the gene expression programs specific for hematopoiesis are still not fully understood. Here, we show that promoter DNA demethylation is associated the activation of hematopoietic-specific genes. Using genome-wide promoter methylation arrays, we identified 694 hematopoietic-specific genes repressed by promoter DNA methylation in human ESCs and whose loss of methylation in hematopoietic can be associated with gene expression. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL8490
34 Samples

Download data: TXT

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Accession:: GSE30090

ID:: 200030090

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000084902.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...