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Items: 4

1.

The role of immunoglobulin A

(Submitter supplied) Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium, and the microbiota. We found that mice lacking B lymphocytes, or lacking IgA, have low intestinal expression of lipid metabolism genes regulated by the transcription factor GATA4, and a consequent decrease in fat absorption in the intestine. The defect disappeared in germ free mice, suggesting that it is dependent on the microbiota; and sequencing analysis of the bacteria showed subtle differences between normal and B-cell deficient mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL14915
20 Samples
Download data: TXT
Series
Accession:
GSE33884
ID:
200033884
2.

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL6480 GPL6806 GPL14915
138 Samples
Download data: TXT
Series
Accession:
GSE23934
ID:
200023934
3.

NIAID Mmeb - Mouse 44k - mAdb [OligID version]

(Submitter supplied) NIAID Mmeb 44k (37.5k reporters) derived from Operon Mouse V4 oligo set. Length 60 bp probe sequences were generated by extracting base 10 through base 69 from the original 70 bp Operon probe. Agilent design number is 017138. For direct access, please contact [email protected]. Protocol: See manufacturer's web site at http://www.agilent.com/
Organism:
Mus musculus
3 Series
32 Samples
Download data
Platform
Accession:
GPL14915
ID:
100014915
4.

control_IgA7

Organism:
Mus musculus
Source name:
control_IgA
Platform:
GPL14915
Series:
GSE23934 GSE33884
Download data: TXT
Sample
Accession:
GSM838354
ID:
300838354
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Supplemental Content

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