GSM929282[Accession] - GEO DataSets

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Items: 4

Select item 2000378741.

Shifted Metabolic Bias in Livers of Mice Lacking Hepatocytic Thioredoxin Reductase-1 Protects Against Acetaminophen Toxicity

(Submitter supplied) Genetic disruption of thioredoxin reductase 1 protects against acetaminophen (APAP) toxicity. To determine the role of the thioredoxin system on xenobiotic metabolism we challeneged wildtype and txnrd1liver-null mice with acetaminophen.

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4928
Platform:: GPL8321
12 Samples

Download data: CEL

Series

Accession:: GSE37874

ID:: 200037874

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49282.

Acetaminophen effect on thioredoxin reductase 1-null liver

Analysis of liver from hepatocyte-specific, thioredoxin reductase 1 (TrxR1)-null mutants treated with the pro-toxin acetaminophen. The Trx system impacts bioenergetics and drug metabolism. Results provide insight into the role of the Trx system in detoxifying certain xenobiotic challenges.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets

Platform:: GPL8321
Series:: GSE37874
12 Samples

Download data: CEL

DataSet

Accession:: GDS4928

ID:: 4928

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000083213.

[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...