GEO DataSets

(Submitter supplied) The liver has inherent regenerative capacity via mitotic division of mature hepatocytes. However, if the hepatic loss is massive or mature hepatocyte proliferation is impaired by chronic liver injury, HSPC are activated to support liver regeneration. Access to liver tissue from 4 patients who underwent liver transplantation for hepatitis B virus (HBV)- associated acute liver failure (ALF) provided us with the opportunity to investigate the molecular mechanisms of liver regeneration in humans by means of gene expression profiling and immunohistochemistry (IHC). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4387

Platform:

GPL570

27 Samples

Download data: CEL

Analysis of explanted livers of 4 patients with HBV-associated ALF who underwent liver transplantation. Liver has inherent regenerative capacity via hepatic stem/progenitor cells (HSPC) when hepatic loss is massive. Results provide insight into role of HSPC in liver regeneration associated with ALF.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 14 individual sets

Platform:

GPL570

Series:

GSE38941

27 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5671 Series

61 Related Platforms

175585 Samples

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