GEO DataSets

Analysis of 3-5 day-old dystrophin-deficient animals exposed to chronic hypoxia (CH) for 2 weeks. Respiratory muscle necrosis in late-stage DMD is associated with respiratory insufficiency and CH. Results provide insight into the effects of CH on dystrophin-deficient muscle in vivo.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 strain, 3 stress sets

Platform:

GPL1322

Series:

GSE15879

16 Samples

Download data: CEL, CHP

Analysis of heads from strains overexpressing Cabut (cbtOE) or depleted for Cabut (cbtRNAi) at two time points during the day-night cycle (i.e., 3 hr after light-on or light-off). Krüppel‐like factors Klf10 and Klf11 are close mammalian homologs of cbt. Results provide insight into role of CBT.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 3 genotype/variation, 2 time sets

Platform:

GPL1322

Series:

GSE67865

6 Samples

Download data: CEL

Analysis of p53 mutant larvae wing imaginal discs up to 18hr after exposure to ionizing radiation (IR). Results provide insight into the molecular mechanisms underlying IR-induced, p53-independent apoptosis in larvae.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol, 2 time sets

Platform:

GPL1322

Series:

GSE37404

16 Samples

Download data: CEL

Analysis of 3rd instar larval brains and imaginal discs that lack centrosomes (DSas-4 and DSas-6) or have too many centrosomes (SakOE). Centrosome defects are common to many cancers. Results provide insight into the effects of centrosome loss or amplification on cell physiology.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 3 genotype/variation, 5 strain sets

Platform:

GPL1322

Series:

GSE35240

15 Samples

Download data: CEL

Analysis of adult females representing segmental deficiencies (Df), both as single Df/+ genotypes and in pairwise Df combinations. Aneuploidies such as segmental monosomy are associated with developmental abnormalities. Results provide insight into the effects of aneuploidies on the transcriptome.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 27 genotype/variation, 8 other sets

Platform:

GPL1322

Series:

GSE34400

44 Samples

Download data: CEL

Analysis of phagocytic receptor Eater depleted hemocyte-derived S2 cells after phagocytosing bacteria for up to 180 minutes. Results provide insight into the role of Eater in the transcriptional regulation of genes that are induced after bacterial binding and phagocytosis.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 agent, 2 genotype/variation, 3 time sets

Platform:

GPL1322

Series:

GSE31564

24 Samples

Download data: CEL

Analysis of female or male genital discs dissected during early morphogenesis (L3, P6, or P20). In flies, the sex-determination hierarchy terminates in the doublesex (dsx) gene. Results provide insight into molecular mechanisms downstream of dsx underlying sex-specific differentiation of genitalia.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 3 development stage, 2 gender sets

Platform:

GPL1322

Series:

GSE23344

24 Samples

Download data: CEL

Analysis of atonal-expressing (atoGFP+) and atoGFP- cells from transgenic wild type and ato-mutant embryos, at 3 time points corresponding to the first 3hr of neural development. Results provide insight into how proneural factors such as ato regulate specialized neuronal differentiation pathways.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 cell type, 3 development stage, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE21520

31 Samples

Download data: CEL

Analysis of heads of animals exposed to ethanol vapor for up to 240 minutes. Increased ethanol intake is facilitated by the development of tolerance to the aversive and pleasurable effects of ethanol. Results provide insight into the molecular mechanisms underlying ethanol tolerance development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 3 agent, 8 time sets

Platform:

GPL1322

Series:

GSE18208

16 Samples

Download data: CEL

Analysis of abdominal and head/thorax segments of mutants lacking p24. Members of the p24 protein family are transmembrane constituents of the ER and Golgi-derived transport vesicles that function in trafficking secretory proteins. Results provide insight into the effect of the loss of p24 function.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation, 2 tissue sets

Platform:

GPL1322

Series:

GSE10940

12 Samples

Download data: CEL

Analysis of embryos lacking the zinc finger protein Zelda. Results provide insight into the role of Zelda in the transfer of control of embryogenesis to the zygotic genome during the process of maternal-to-zygotic transition.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE11231

6 Samples

Download data: CEL

Analysis of heads of Canton-S males subjected to social isolation (single-housed). Social experience with conspecifics is an environmental influence on aggressiveness common to many species. Results provide insight into the molecular basis of the effect of social experience on aggressiveness.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL1322

Series:

GSE6994

6 Samples

Download data: CEL, CHP

Analysis of alcohol resistant and sensitive strains. Strains generated by artificial selection for alcohol sensitivity over multiple generations. Results provide insight into the molecular basis of alcohol sensitivity.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 gender, 2 other, 3 strain sets

Platform:

GPL1322

Series:

GSE7614

24 Samples

Download data: CEL, CHP

Analysis of 5 and 8 hour embryos from 9 inbred lines. Results provide insight into the extent of gene expression variation in natural populations during early development.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 age, 9 strain sets

Platform:

GPL1322

Series:

GSE8892

36 Samples

Download data: CEL, CHP

Analysis of eight distinct adult tissues in a model organism. Two larval tissues and whole organism also examined. Results provide insight into the degree of tissue specific gene expression at the adult stage.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 development stage, 11 tissue sets

Platform:

GPL1322

Series:

GSE7763

44 Samples

Download data: CEL, CHP, XML

Analysis of third instar larvae lacking noncoding RNAs roX1 and roX2. The roX RNAs are components of the male-specific lethal (MSL) ribonucleoprotein complex, required for equalization of X:A expression levels in males. Results provide insight into the role of roX RNAs in X-chromosome expression.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE3990

6 Samples

Download data: CEL

Comparison of ovaries from bag of marbles (bam) mutants and stonewall (stwl) bam double mutants. Stwl is a DNA-associated protein required for germline stem cell (GSC) maintenance; Bam is a key differentiation factor. Results provide insight into the role of Stwl in maintaining germ cell identity.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE6928

6 Samples

Download data: CEL

Analysis of first instar larvae containing a chromosome 4 specific protein POF D119 mutation. POF is an autosome-specific protein that regulates gene expression in chromosome 4 in its entirety. Results provide insight into the molecular mechanisms that regulate chromosome 4 specific gene expression.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL1322

Series:

GSE6839

6 Samples

Download data: CEL

Analysis of alcohol-sensitive Canton S animals immediately following ethanol exposure and a population of Canton S animals that developed tolerance 2 hours after ethanol exposure. Results provide insight into the underlying cellular and physiological mechanisms that respond to alcohol exposure.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 agent, 3 protocol, 2 strain sets

Platform:

GPL1322

Series:

GSE5382

15 Samples

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Analysis of transgenic larvae overexpressing the nuclear receptor DHR96, an ortholog of the xenobiotic nuclear receptors pregnane X receptor and constitutive androstane receptor. Results provide insight into the role of DHR96 in regulating xenobiotic responses.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL1322

Series:

GSE5097

6 Samples

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