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Links from GEO DataSets

Items: 1 to 20 of 23

1.
Full record GDS4250

Artificial medium mimicking cystic fibrosis lung sputum

Analysis of Pseudomonas aeruginosa UCBPP-PA14 grown on artificial-sputum medium (ASMDM), MOPS-glucose medium and Luria broth; early exponential and stationary phases. ASMDM mimics cystic fibrosis lung environment.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa UCBPP-PA14
Type:
Expression profiling by array, transformed count, 3 growth protocol, 2 time sets
Platform:
GPL84
Series:
GSE18594
8 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS4250
ID:
4250
2.
Full record GDS5165

PA2449 deficiency effect on Pseudomonas aeruginosa PAO1

Analysis of Pseudomonas aeruginosa PAO1 cells deficient for the transcription factor PA2449. Results provide insight into the role of PA2449 in the metabolism and physiology of Pseudomonas.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL84
Series:
GSE39044
8 Samples
Download data: CEL
3.
Full record GDS4959

Pseudomonas aeruginosa sphR deficient mutant response to lung surfactant

Analysis of P. aeruginosa sphR null mutants grown in media containing lung surfactant. P. aeruginosa is an opportunistic pathogen of the human lung. SphR is an AraC-family transcription factor. Results provide insight into the role of sphR in P. aeruginosa infections in the lung.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL84
Series:
GSE48982
8 Samples
Download data: CEL
4.
Full record GDS4958

Pseudomonas aeruginosa response to lung surfactant

Analysis of P. aeruginosa grown in media containing lung surfactant. P. aeruginosa is a common environmental bacterium that is also an opportunistic pathogen, particularly of the human lung. Results provide insight into the mechanisms used by P. aeruginosa to establish and maintain lung infections.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL84
Series:
GSE48982
4 Samples
Download data: CEL
5.
Full record GDS4480

Isolates from chronically-infected burn wound and cystic fibrosis patients

Analysis of P. aeruginosa strains isolated from chronically-infected lungs of cystic fibrosis (CF) patients, burn wounds, and a burn wound strain infected-murine tumor model. Results provide insight into the molecular mechanisms underlying chronic biofilm-associated P. aeruginosa infections.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 4 isolate, 2 other, 5 strain sets
Platform:
GPL84
Series:
GSE25945
26 Samples
Download data: CEL
DataSet
Accession:
GDS4480
ID:
4480
6.
Full record GDS4479

Isolates from burn wound patients

Analysis of three different P. aeruginosa strains isolated from burn wound patients and the same strains using two infection models (a plant model and a murine tumor model). Results provide insight into the molecular mechanisms underlying P. aeruginosa infections.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 5 isolate, 3 strain sets
Platform:
GPL84
Series:
GSE23007
30 Samples
Download data: CEL
7.
Full record GDS4457

Strain PAO1 response to natural quorum sensing inhibitor protoanemonin

Analysis of laboratory strain PAO1 treated with 125μM protoanemonin (4-methylenebut-2-en-4-olide), a natural quorum sensing (QS) inhibitor. Results provide insight into the molecular mechanisms underlying protoanemonin inhibition of QS in P. aeruginosa.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL84
Series:
GSE27674
4 Samples
Download data: CEL
DataSet
Accession:
GDS4457
ID:
4457
8.
Full record GDS4254

KinB and RpoN deletion effects on alginate overproduction

Analysis of Pseudomonas aeruginosa PAO1 mucoid kinB mutant and nonmucoid kinB rpoN double mutant. Deletion of the sensor kinase KinB results in alginate overproduction, a trait associated with chronic endobronchial infections in cystic fibrosis. Sigma Factor RpoN is required for mucoid induction.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL84
Series:
GSE35248
6 Samples
Download data: CEL, CHP
9.
Full record GDS4249

Chronological clonal isolates from sputum or throat samples of cystic fibrosis patients

Analysis of clonal isolates collected from three patients with cystic fibrosis (CF). The isolates were collected between 3 months to 8 years after colonization, representing upwards of 39,000 in vivo generations. Results provide insight into the molecular basis of long-term infection of CF lung.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 4 individual, 19 isolate, 3 other, 4 time sets
Platform:
GPL84
Series:
GSE21966
38 Samples
Download data: CEL
10.
Full record GDS4244

Antibiotic-resistant Small Colony Variant

Analysis of Pseudomonas aeruginosa PA01 (ATCC 15692) Small Colony Variant (SCV). SCVs are slow-growing bacteria that often show increased resistance to antibiotics and cause infection. Results provide insight into mechanisms governing acquisition and reversion of antibiotic resistance in bacteria.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 time sets
Platform:
GPL84
Series:
GSE34141
12 Samples
Download data: CEL
11.
Full record GDS3572

Pseduomonas aeruginosa PAO1 response to subinhibitory colistin

Analysis of Pseduomonas aeruginosa PAO1 treated with colistin at a subinhibitory concentration (0.15 ug/ml). Colistin is an antimicrobial peptide against P. aeruginosa infection in cystic fibrosis lungs. Result provide insight into the adaptive response of P. aeruginosa to low doses of colistin.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL84
Series:
GSE13252
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3572
ID:
3572
12.
Full record GDS3562

Azithromycin effect on Pseudomonas aeruginosa PAO1

Analysis of PAO1 cultures exposed to up to 2.0 ug/ml of the macrolide azithromycin (AZM) for 9 hours. Low-dose macrolides are effective therapy in patients with chronic lung infections such as those caused by P. aeruginosa. Results provide insight into mechanism of action of AZM against infection.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 2 agent, 3 dose sets
Platform:
GPL84
Series:
GSE12738
5 Samples
Download data: CEL
DataSet
Accession:
GDS3562
ID:
3562
13.
Full record GDS3251

Comparison of tobramycin-treated PA14 biofilm/CFBE and planktonic cultures

Analysis of PA14 biofilms grown on cystic fibrosis bronchial epithelial (CFBE) cells and PA14 planktonic cultures treated with tobramycin, a CF antibiotic treatment. Results provide insight into P14 infection in the context of CFBEs and suggest P14's response to tobramycin is growth mode-dependent.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 2 agent, 2 cell type sets
Platform:
GPL84
Series:
GSE10030
10 Samples
Download data: CEL, CHP
14.
Full record GDS3174

Pseudomonas aeruginosa non-mucoid and mucoid strains

Analysis of a non-mucoid Pseudomonas aeruginosa strain and a mucoid strain from a cystic fibrosis (CF) patient. P. aeruginosa is an opportunistic pathogen associated with chronic pulmonary infections in CF patients. Non-mucoidity is associated with early stages of CF, mucoidity with late stages.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 2 strain sets
Platform:
GPL84
Series:
GSE9621
4 Samples
Download data: CEL, CHP, EXP
DataSet
Accession:
GDS3174
ID:
3174
15.
Full record GDS2893

Response to low oxygen conditions

Analysis of Pseudomonas aeruginosa strain PAO1 grown with 2% or 0.4% oxygen (O2), or without O2 but with nitrate instead. In cystic fibrosis (CF) lungs, PAO1 grows to high densities in mucopurulent material depleted in O2. Results provide insight into mode of growth in CF lungs.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 4 dose, 3 stress sets
Platform:
GPL84
Series:
GSE6741
8 Samples
Download data: CEL
16.
Full record GDS2870

Pseudomonas aeruginosa cystic fibrosis isolate response to various sulfur sources

Analysis of Pseudomonas aeruginosa E601 grown in media containing various sources of sulfur. P. aeruginosa E601 is a cystic fibrosis isolate that exhibits mucin sulfatase activity. Results provide insight into the pathways that respond to the nature of the supply of sulfur.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, transformed count, 5 growth protocol, 2 strain sets
Platform:
GPL84
Series:
GSE8408
20 Samples
Download data: CEL
17.
Full record GDS2869

Pseudomonas aeruginosa from cystic fibrosis lungs

Analysis of Pseudomonas aeruginosa isolates from sputa of cystic fibrosis (CF) lungs following growth in minimal media. P. aeruginosa infected CF lungs are characterized by high cell density (HCD) replication of this pathogen. Results provide insight into the mechanisms sustaining HCD replication.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 4 growth protocol, 2 protocol, 3 specimen sets
Platform:
GPL84
Series:
GSE7704
14 Samples
Download data: CEL, CHP
18.
Full record GDS2764

Pseudomonas aeruginosa response to 3,4-(di)hydroxy-heptyl-quinoline: time course

Analysis of Pseudomonas aeruginosa cells treated for up to 20 hours with 3,4-(di)hydroxy-heptyl-quinoline (PQS), a bacterial intercellular signaling molecule. Results provide insight into the role of PQS in the bacterial communication system termed quorum sensing.
Organism:
Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1
Type:
Expression profiling by array, count, 2 agent, 3 time sets
Platform:
GPL84
Series:
GSE3836
12 Samples
Download data
DataSet
Accession:
GDS2764
ID:
2764
19.
Full record GDS2502

Pseudomonas aeruginosa response to airway epithelia

Analysis of Pseudomonas aeruginosa PAO1 or Type III secretion system (TTSS), rhamnolipid synthesis double mutant strain exposed to cultured airway epithelia. TTSS is a virulence factor in acute infections. Strains from chronic infections express decreased levels of TTSS or lack a functional TTSS.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 2 agent, 2 strain sets
Platform:
GPL84
Series:
GSE4614
8 Samples
Download data
20.
Full record GDS2377

Response to copper stress conditions

Analysis of cells subjected to elevated copper (Cu) for 45 minutes (Cu shock) or grown in the presence of elevated Cu for 6 hours (Cu adapted). Industrial activity results in elevated levels of environmental Cu. Results provide insight into the molecular response of P. aeruginosa to Cu stress.
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array, count, 2 protocol, 4 stress sets
Platform:
GPL84
Series:
GSE4152
8 Samples
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