GEO DataSets

Analysis of Escherichia coli cells treated with a sublethal concentration of the antimicrobial arylamide compound PMX 10070 for 20 and 60 minutes. Arylamides permeabilize E. coli membranes. Results provide insight into molecular mechanisms underlying the antibacterial action of arylamides.

Organism:

Escherichia coli

Type:

Expression profiling by array, count, 3 agent, 2 time sets

Platform:

GPL3154

Series:

GSE31140

18 Samples

Download data: CEL, CHP

Analysis of Hpx- (ahpCF::kanR, katG, katE) triple deletion mutant. H202 scavenging is performed by the three hydrogen enzymes: alkyl hydroperoxidase reductase (AhpCF), catalase G (KatG) and catalase E (KatE). Results provide insight into molecular basis of the oxidative stress response in bacteria.

Organism:

Escherichia coli; Escherichia coli str. K-12 substr. MG1655

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL3154

Series:

GSE56133

6 Samples

Download data: CEL

Analysis of Δfur and wildtype cells treated with the bacterial antibiotic gentamicin and harvested 1 hr post-treatment. Fur is the master regulator of iron metabolism in E. coli. Results provide insight into Fur's influence on the magnitude of stress responses triggered by bactericidal antibiotics.

Organism:

Escherichia coli; Escherichia coli str. K-12 substr. MG1655

Type:

Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets

Platform:

GPL3154

Series:

GSE56133

12 Samples

Download data: CEL

Analysis of wild-type cells treated with various antibiotics or hydrogen peroxide and harvested 1 hour post-treatment. Results provide insight into the molecular mechanisms underlying antibiotic lethality.

Organism:

Escherichia coli; Escherichia coli str. K-12 substr. MG1655

Type:

Expression profiling by array, transformed count, 6 agent sets

Platform:

GPL3154

Series:

GSE56133

18 Samples

Download data: CEL

Analysis of E. coli O157:H7 exposed to cinnamaldehyde (CIN) for up to 4 hours. CIN is a natural antimicrobial effective against many foodborne pathogens including Escherichia coli O157:H7. Results provide insight into molecular processes underlying CIN-induced transient inhibition of E. coli.

Organism:

Escherichia coli; Escherichia coli O157:H7

Type:

Expression profiling by array, transformed count, 2 agent, 2 time sets

Platform:

GPL3154

Series:

GSE40693

8 Samples

Download data: CEL

Analysis of Escherichia coli cells treated with CHIR-090, an inhibitor of lipid A bioynthesis, to increase the ratio of saturated to unsaturated fatty acids (SFA:UFA) in the cell membrane. Results provide insight into molecular mechanisms regulating membrane lipid homeostasis in E. coli.

Organism:

Escherichia coli

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL3154

Series:

GSE18623

6 Samples

Download data: CEL

Analysis of bacterial Frag1 cells subjected to ionic (NaCl) and non-ionic (sucrose) hyperosmotic stress (HS). Results provide insight into the molecular mechanisms underlying the specificity of osmotic adjustment to ionic and non-ionic osmotica.

Organism:

Escherichia coli

Type:

Expression profiling by array, count, 3 stress sets

Platform:

GPL3154

Series:

GSE12190

6 Samples

Download data: CEL, CHP

Analysis of enterohemmorhagic Escherichia coli (EHEC) O157:H7 treated with epinephrine (EP), norepinephrine (NE), and indole. During infection in the gastrointestinal tract, EHEC is exposed to a wide range of signaling molecules such as EP and NE, and bacterial signaling molecules such as indole.

Organism:

Escherichia coli

Type:

Expression profiling by array, count, 4 agent sets

Platform:

GPL3154

Series:

GSE5552

4 Samples

Download data: CEL, RPT

Analysis of enterohemorrhagic Escherichia coli biofilm treated with 7-hydroxyindole or oxidized indole (isatin). Many bacterial oxygenases readily convert indole, an interspecies biofilm signal, into oxidized compounds. Results provide insight into the role of oxidized indoles in biofilm formation.

Organism:

Escherichia coli

Type:

Expression profiling by array, count, 3 agent, 2 cell type sets

Platform:

GPL3154

Series:

GSE6195

4 Samples

Download data: CEL