|
| Status |
Public on Oct 20, 2009 |
| Title |
E. coli gene expression following CHIR-090 treatment |
| Organism |
Escherichia coli |
| Experiment type |
Expression profiling by array
|
| Summary |
CHIR-090 is an inhibitor of lipid A biosytnesis. CHIR-090 treatment on E. coli sinificantly increased the expression of fatty acid biosythesis gene fabA and fabB.
Keywords: Inhibition response
|
| |
|
| Overall design |
The lipid A biosynthesis in E. coli was inhibited by CHIR-090, and the RNA was extracted after 10 minutes treatment to capture the effect of increased saturated fatty acid on global gene expression.
|
| |
|
| Contributor(s) |
Zhu K, Zhang Y, Frank MW, Miller K, Rock CO |
| Citation(s) |
19854834 |
| |
| Submission date |
Oct 19, 2009 |
| Last update date |
Mar 08, 2019 |
| Contact name |
Matthew Wilmer Frank |
| E-mail(s) |
[email protected]
|
| Phone |
901-595-5614
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Infectious Diseases
|
| Lab |
Dr. Charles Rock
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL3154 |
[E_coli_2] Affymetrix E. coli Genome 2.0 Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA121459 |
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