GEO DataSets

Analysis of 12 distinct neuronal subpopulations from 5 regions of the adult forebrain. Results identify highly heterogeneous expression profiles that likely underlie the fundamental differences observed between neuronal classes and between glutamatergic and GABAergic neurons within a given class.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type, 6 tissue sets

Platform:

GPL339

Series:

GSE2882

42 Samples

Download data: CEL, EXP, RPT

(Submitter supplied) The mammalian forebrain is a tissue of stunning complexity comprised of numerous regions each containing many distinct cell types that differ in their intrinsic and synaptic physiology, morphology and connectivity. These differences are likely conferred by differential gene expression, but the extent and nature of cell type specific gene expression is largely unknown. Here, we carried out microarray analysis of twelve major classes of fluorescently labelled neurons within the forebrain and provide the first comprehensive view of gene expression differences. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS1522

Platform:

GPL339

42 Samples

Download data: CEL, EXP, RPT

(Submitter supplied) Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturbations. To establish the generality of this approach, we present translational profiles for twenty four CNS cell populations, and identify known cell-specific and enriched transcripts for each population. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

107 Samples

Download data: CEL