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Series GSE2882 Query DataSets for GSE2882
Status Public on Dec 15, 2005
Title Cell type specific expression profiles of mouse forebrain neurons
Organism Mus musculus
Experiment type Expression profiling by array
Summary The mammalian forebrain is a tissue of stunning complexity comprised of numerous regions each containing many distinct cell types that differ in their intrinsic and synaptic physiology, morphology and connectivity. These differences are likely conferred by differential gene expression, but the extent and nature of cell type specific gene expression is largely unknown. Here, we carried out microarray analysis of twelve major classes of fluorescently labelled neurons within the forebrain and provide the first comprehensive view of gene expression differences. The results demonstrate a profound molecular heterogeneity among neuronal subtypes, represented disproportionately by gene paralogs, and begin to reveal the genetic programs underlying the fundamental divisions between neuronal classes including that between glutamatergic and GABAergic neurons.
Keywords: cell type comparison
 
Overall design Total of 36 samples from 12 different cell types were anlyzed. Three biological replicates (each sample from different animal(s)) were analyzed for each cell type.
Web link http://mouse.bio.brandeis.edu
 
Contributor(s) Sugino K, Hempel CM, Nelson SB
Citation(s) 16369481
Submission date Jul 05, 2005
Last update date Jan 08, 2019
Contact name Ken Sugino
Organization name Janelia Research Campus
Lab NeuroSeq
Street address 19700 Helix Dr
City Ashburn
State/province VA
ZIP/Postal code 20147
Country USA
 
Platforms (1)
GPL339 [MOE430A] Affymetrix Mouse Expression 430A Array
Samples (42)
GSM63015 GIN-Hippocampus replicate1
GSM63016 GIN-Hippocampus replicate2
GSM63017 GIN-Hippocampus replicate3
Relations
BioProject PRJNA92571

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE2882_RAW.tar 144.7 Mb (http)(custom) TAR (of CEL, EXP, RPT)

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