GEO DataSets

Analysis of colon carcinoma Caco-2 cells cultured for various lengths of time up to 3 weeks in flasks or on filters. An array focusing on transporters and ion channels was used. Results provide insight into the influence of cell differentiation on the mRNA expression of transporters and channels.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 2 protocol, 4 time sets

Platform:

GPL1213

Series:

GSE1368

32 Samples

Download data

(Submitter supplied) Genomic profile of transporters and ion channels in differentiated or undifferentiated Caco-2 cells grown for 5 days, 1 week, 2 weeks or 3 weeks in flasks or filters Keywords: ordered

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1993

Platform:

GPL1213

32 Samples

Download data

(Submitter supplied) Custom array chip focusing on transporters and ion channels. Genes are represented by 70 mers.

Organism:

Homo sapiens

1 DataSet

1 Series

32 Samples

Download data

(Submitter supplied) The aim was to investigate mechanisms contributing to quercetin’s previously described effects on cell-proliferation and -differentiation, which contradicted its proposed anti-carcinogenic potency. In a 10-day experiment, 40 µM quercetin stabilized by 1mM ascorbate reduced Caco-2 differentiation up to 50% (P<0.001). Caco-2 RNA from days 5 and 10, hybridized on HG-U133A2.0 Affymetrix® GeneChips®, showed 1,743 affected genes on both days (P<0.01). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3032

Platform:

GPL571

8 Samples

Download data: CEL, CHP

Analysis of post-confluent Caco-2 colon cancer cells up to 10 days after treatment with ascorbate-stabilized quercetin, a polyphenol antioxidant compound. Caco-2 cells differentiate after reaching confluency. Results provide insight into quercetin's role in cell-proliferation and -differentiation.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL571

Series:

GSE7259

8 Samples

Download data: CEL, CHP

(Submitter supplied) Transcriptional profile of 21-days differentiated Caco-2 cells compared to Caco-2 cycling cells. Goal was to demonstrate the ability of Caco-2 cells to express most of the markers typical of differentiated enterocytes. A novel protocol of line maintenance was used.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6848

4 Samples

Download data: TXT

(Submitter supplied) Transcriptional profile of 21-days differentiated LD Caco-2 cells compared to 21-days differentiated HD Caco-2 cells. Goal was to find some differences in the genome profile of the LD and HD Caco-2 cells that could be addressed to the different protocols used for the line maintenance.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6480

2 Samples

Download data: TXT

(Submitter supplied) This series of microarray experiments monitored the gene expression profiles for monoclonal cell lines (derived from HEK-293 parental cell culture) with high (H1, H15, H24, H36, H39) or low (L3, L28, L29) levels of store-operated Ca2+ entry (SOCE). For selection of clones, HEK-293 cells were loaded with indo-1 and sorted by FACS on the basis of their cyclopiazonic acid (CPA)-stimulated Ca2+ entry. Monoclonal cell lines were selected from the sorted cells and their levels of SOCE confirmed by monitoring thapsigargin-stimulated Ba2+ entry. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS686

Platform:

GPL96

22 Samples

Download data

Comparison of HEK-293-derived monoclonal cell lines with high or low levels of store-operated Ca2+ entry (SOCE). Levels of SOCE confirmed by monitoring thapsigargin-stimulated Ba2+ entry.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 9 cell line, 3 other sets

Platform:

GPL96

Series:

GSE1309

22 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and in house platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

9 related Platforms

91 Samples

Download data: CEL, TIFF

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3734

20 Samples

Download data: TIFF

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3761

5 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3760

20 Samples

Download data: TIFF

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3757

5 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3759

5 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL3758

5 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL922

5 Samples

Download data

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL81

16 Samples

Download data: CEL

(Submitter supplied) Gene expression microarrays have made a profound impact in biomedical research. The diversity of platforms and analytical methods has made comparison of data from multiple platforms very challenging. In this study, we describe a framework for comparisons across platforms and laboratories. We have attempted to include nearly all the available commercial and “in-house” platforms. Using probe sequences matched at the exon level improved consistency of measurements across the different microarray platforms compared to annotation-based matches. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2995

10 Samples

Download data

(Submitter supplied) The raw data are presented. The computations in the manuscript were based on the fold-changes reported by the MAS 4.0 software, not on ratios taken from raw data Keywords: parallel sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1847

Platform:

GPL8300

10 Samples

Download data