GEO DataSets

(Submitter supplied) Develop of the heart during perinatal period must involve the differentially expression of a myriad of genes. We can think about the developmental events of heart formation in the context of genetic networks. However the knowledge of the genetic basis in governing and regulating of this development is still partial and scattered; an overall elucidation of the differential expressed genes blueprint before and after birth has never been proposed. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5918

5 Samples

Download data: TXT

(Submitter supplied) Drought, salinity and sub-optimal temperatures are stresses that cause adverse effects on the growth of plants and the productivity of crops. In this study, we have analyzed the expression profiles of rice genes under control and abiotic stress conditions using microarray technology to identify the genes differentially expressed during various abiotic stresses. Keywords: Stress treatment

Organism:

Oryza sativa

Type:

Expression profiling by array

Platform:

GPL2025

12 Samples

Download data: CEL

(Submitter supplied) Plants initially undergo a period of vegetative development, in which it produces leaves from shoot apical meristem (SAM) and roots from the root apical meristem. Later in development, the SAM undergoes a change in fate and enters reproductive development called as floral transition, producing flowers and seeds. Our understanding of the molecular and genetic mechanisms that underlie reproductive development in plants has increased tremendously in the past decade, essentially through the work on Arabidopsis. more...

Organism:

Oryza sativa

Type:

Expression profiling by array

Platform:

GPL2025

45 Samples

Download data: CEL

(Submitter supplied) Indica rice seedlings of IR64 variety were grown hydroponically for 7-days in a culture room with a daily photoperiodic cycle of 14h light and 10h dark. Seedlings were incubated in 0.1% dimethyl sulfoxide (control) or 50 micromolar solutions of indole-3-acetic acid (IAA treatment) and benzyl aminopurine (BAP treatment) for 1h and 3h. Equal amounts of 1h and 3h samoles were pooled for each treatment before RNA isolation. more...

Organism:

Oryza sativa

Type:

Expression profiling by array

Platform:

GPL2025

6 Samples

Download data: CAB, CEL, EXP

(Submitter supplied) This study aimed to identify genes that are linked with optineurin expression using a combined siRNA-microarray approach Keywords: siRNA treatment study

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2892

Platform:

GPL570

6 Samples

Download data: CEL

Analysis of HeLa cells depleted for optineurin using RNAi knockdown. Mutations in the gene for optineurin are associated with open-angle glaucoma. Results provide insight into the function of optineurin and its role in the pathogenesis of open-angle glaucoma.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol sets

Platform:

GPL570

Series:

GSE6819

6 Samples

Download data: CEL

(Submitter supplied) The biological mechanisms by which cerebral aneurysms emerge, enlarge and rupture are not totally understood. In the present study, we analyzed the genome-wide gene expression profile in human intracranial aneurysms using cDNA microarrays.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3903

Platform:

GPL570

6 Samples

Download data: CEL

Analysis of unruptured intracranial arterial aneurysm (IAA). IAA is a cerebrovascular disorder in which weakness in a cerebral artery wall causes localized dilation and possible rupture. Results provide insight into the molecular mechanisms underlying cerebral aneurysms.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL570

Series:

GSE26969

6 Samples

Download data: CEL

(Submitter supplied) The limbus is a unique anatomic structure that is highly innervated and vascularized yet sets the boundary for the avascularized cornea. The corneal epithelial stem cells are believed to reside at the limbus. The intrinsic and external molecular signals that modulate the differentiation and proliferation of the limbal stems cells are still largely unidentified because of a lack of known specific markers. more...

Organism:

Homo sapiens; Chlorocebus sabaeus

Type:

Expression profiling by array

Platform:

GPL570

3 Samples

Download data: CEL

(Submitter supplied) To understand the host transcriptional response to S. enterica serovar Choleraesuis (S. Choleraesuis), the first generation Affymetrix porcine GeneChip® was used to identify differentially expressed genes in the mesenteric lymph nodes responding to infection at acute (8 hours (h), 24h, 48h post-inoculation (pi)) and chronic stages (21 days (d) pi) The objectives of this study were to identify and examine the stereotypical gene expression response within the host mesenteric lymph nodes to S. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

15 Samples

Download data: CEL, EXP

(Submitter supplied) Prostaglandin F2 alpha (PGF2alpha) brings about regression of the bovine corpus luteum (CL). This luteolytic property of PGF2alpha is used in the beef and dairy cattle to synchronize estrus. A limitation of this protocol is an insensitivity of the early CL to luteolytic actions of PGF2alpha. The mechanisms underlying luteal sensitivity (LS) are poorly understood. The early CL has maximum number of PGF2alpha receptors; therefore differences in signaling events might be responsible for LS. more...

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL3810

1 Sample

Download data: GPR

(Submitter supplied) In order to study the gene expression profiles of monocyte and macrophages, we collected three type of cells and performed pair-wised comparison. It includes human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar macrophages (BAL). All the experiments are performed comparing two of the three cell types from the same person (total 4 persons). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3966 GPL3967

96 Samples

Download data

(Submitter supplied) Endocardial (EE) and Aortic (AE) endothelial cells were isolated from the same two rats, pooled (EE and AE kept separately) and cultured for 2 passages. Culture conditions and confluence of EE and AE cell cultures were kept as identical as possible. RNA was isolated and the expression profile of both endothelial cell types was compared using the Affymetrix rat genome U34A array. Keywords: parallel sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS695

Platform:

GPL85

2 Samples

Download data: CEL, EXP, RPT

Gene expression profiles of endocardial (EE) and aortic (AE) endothelial cells. EE and AE genetic diversity in culture reflects in vivo physiological diversity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL85

Series:

GSE1478

2 Samples

Download data: CEL, EXP, RPT

(Submitter supplied) Aerobic capacity is a strong predictor of cardiovascular mortality. To determine the relationship between aerobic capacity and cardiac gene expression we examined genome-wide gene expression in hearts of rats artificially selected for high- and low running capacity (HCR and LCR, respectively) over 16 generations. HCR were born with an athletic phenotype, whereas LCR exhibited features of the metabolic syndrome. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3131

Platform:

GPL1355

16 Samples

Download data: CEL

Analysis of hearts from low (LCRs) and high capacity runners (HCRs) with or without exercise training. Aerobic capacity is a strong predictor of cardiovascular mortality. Results provide insight into the molecular basis for the difference in inborn aerobic capacity in the LCRs and HCRs.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 protocol, 2 strain sets

Platform:

GPL1355

Series:

GSE9445

16 Samples

Download data: CEL

(Submitter supplied) Ischemic cardiopathy is the leading cause of death in the world, for which efficient regenerative therapy is not currently available. In mammals, after a myocardial infarction episode, the damaged myocardium is replaced by scar tissue featuring collagen deposition and tissue remodelling with negligible cardiomyocyte proliferation. Zebrafish, in contrast, display an extensive regenerative capacity as they are able to restore completely lost cardiac tissue after partial ventricular amputation. more...

Organism:

Danio rerio

Type:

Expression profiling by array

Dataset:

GDS3623

Platform:

GPL1319

15 Samples

Download data: CEL

Analysis of hearts of zebrafish 1 to 7 days following partial heart amputation. Unlike mammals, zebrafish hearts display an extensive regenerative capacity. Results provide insight into the molecular basis of this regenerative capacity.

Organism:

Danio rerio

Type:

Expression profiling by array, transformed count, 2 protocol, 5 time sets

Platform:

GPL1319

Series:

GSE17993

15 Samples

Download data: CEL

(Submitter supplied) Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression.<BR> <LI><u>Brain:</u></LI><BR> GSM2558: Control<bR> GSM2559: Control <bR> GSM2560: Fungal oil (AA)<bR> GSM2561: Fungal oil (AA)<bR> GSM2562: Fish oil (DHA)<bR> GSM2563: Fish oil (DHA)<bR> GSM2564: Fish and Fungal oil (DHA + AA)<bR> <LI><u>Liver:</u></LI><bR> GSM2565: Control <bR> GSM2566: Control<bR> GSM2567: Control<bR> GSM2568: Control<bR> GSM2569: Fungal oil (AA)<bR> GSM2570: Fungal oil (AA)<bR> GSM2571: Fish oil (DHA)<bR> GSM2572: Fish oil (DHA)<bR> GSM2573: Fish + Fungal oil (DHA +AA)<bR> GSM2574: Fish + Fungal oil (DHA +AA)<bR> Keywords: ordered

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS168 GDS169

Platforms:

GPL76 GPL75

17 Samples

Download data

Dietary effects of long chain polyunsaturated fatty acids from arachidonate-rich fungal oil and fish oil on hepatic and hippocampal gene expression. Identified broad-spectrum effects on major lipid metabolism transcription factors.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 4 protocol, 2 tissue sets

Platform:

GPL76

Series:

GSE91

9 Samples

Download data