Similar studies for GEO DataSets (Select 200010128) - GEO DataSets

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Items: 20

Select item 2000101281.

Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer

(Submitter supplied) Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess copy number changes in 31 pairs of clinicopathologically well matched recurred / nonrecurred breast cancer tissues. Keywords: array CGH

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
62 Samples

Download data: GPR

Series

Accession:: GSE10128

ID:: 200010128

Select item 2000101812.

Genomic copy number alterations as predictive markers in breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
118 Samples

Download data: GPR

Series

Accession:: GSE10181

ID:: 200010181

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000101293.

Genomic copy number alterations as predictive markers of neoadjuvant chemotherapy response in breast cancer

(Submitter supplied) Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess different copy number changes between chemotherapy responsive and non-resposive breast cancer tissues. Keywords: Array CGH

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
56 Samples

Download data: GPR

Series

Accession:: GSE10129

ID:: 200010129

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000059274.

SNP expression data from breast cancer

(Submitter supplied) SNP Expression profiling of human breast cancer: 29 tumor samples, 4 pure normal breat samples and 8 lymphocytes samples Keywords: Human Cancer

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platform:: GPL2005
41 Samples

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Series

Accession:: GSE5927

ID:: 200005927

PubMed Similar studies

Select item 2000136965.

Copy number profiling of 45 human breast cancer cell lines on Affymetrix 100K SNP arrays

(Submitter supplied) Breast cancer cell lines grown in full serum under standard conditions were profiled on Affymetrix GeneChip Mapping 100K Set Arrays Keywords: Mapping Array

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platforms:: GPL2004 GPL2005
90 Samples

Download data: CEL

Series

Accession:: GSE13696

ID:: 200013696

PubMed Similar studies

Select item 2000065676.

Chromosome 8 BAC Array CGH and Expression Studies Identify Amplification and Overexpression of TRMT12 in Breast Cancer

(Submitter supplied) Genomic changes in chromosome 8 are commonly observed in breast cancer cell lines and tumors. Fine mapping of such genomic changes, and evaluation of associated expression changes, are expected to provide reagents for diagnosis, insights into understanding the disease, and open up avenues for novel therapeutic intervention. We made an effort to search for genes on chromosome 8 with altered copy number and expression. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by genome tiling array

Platforms:: GPL4615 GPL4611
42 Samples

Download data: TXT

Series

Accession:: GSE6567

ID:: 200006567

Select item 2000315197.

A Clinically Relevant Gene Signature in Triple-Negative and Basal-Like Breast Cancer

(Submitter supplied) Current prognostic gene expression profiles for breast cancer mainly reflect proliferation status and are most useful in ER-positive cancers. Triple-negative breast cancers (TNBCs) are clinically heterogeneous, and prognostic markers and biology-based therapies are needed to better treat this disease. We assembled Affymetrix gene expression data for 579 TNBCs and performed unsupervised analysis to define metagenes that distinguish molecular subsets within TNBC. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Third-party reanalysis

Platform:: GPL96
67 Samples

Download data: CEL, TXT

Series

Accession:: GSE31519

ID:: 200031519

PubMed Full text in PMC Similar studies

Select item 1000014328.

6k-array, version 3/4.

(Submitter supplied) Whole-genome BAC-array. Isolated BAC-DNA was amplified by two-step DOP-PCR. PCR products were dissolved in 3xSSC, 1.5M betaine and spotted as triplicates on epoxysilane-coated slides. Keywords = Matrix-CGH Keywords = array-CGH

Organism:: Homo sapiens

1 Series
94 Samples

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Platform

Accession:: GPL1432

ID:: 100001432

PubMed Similar studies

Select item 2000067469.

High-resolution genomic profiles of breast cancer cell lines

(Submitter supplied) A BAC-array platform for comparative genomic hybridization was constructed from a library of 32,433 clones providing complete genome coverage, and evaluated by screening for DNA copy number changes in 11 breast cell lines (BT474, MCF7, HCC1937, SK-BR-3, L56Br-C1, ZR-75-1, MCF10A, JIMT1, MDA-MB-231, MDA-MB-361 and HCC2218). These were also characterized by gene expression analysis and found to represent all five recently described breast cancer subtypes using the ‘intrinsic gene set’ and centroid correlation. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL4723
11 Samples

Download data: TXT

Series

Accession:: GSE6746

ID:: 200006746

Select item 20001009910.

Multi-dimensional genomic analysis in breast cancer patients

(Submitter supplied) Multi-dimensional genomic analysis identifies a class of breast cancer patients with high metastatic outcome and differential response to chemotherapeutic drugs The application of multi-dimensional genomic analyses might provide a more refined risk assessment of breast tumor aggressiveness and improve the selection of patients for personalized medicine. Our study demonstrates the feasibility of using CNAs to predict patient outcome. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platforms:: GPL2005 GPL2004
626 Samples

Download data: CEL

Series

Accession:: GSE10099

ID:: 200010099

PubMed Similar studies

Select item 20000875711.

High resolution array-CGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer

(Submitter supplied) An oligo array based high-resolution analysis of copy number alterations in 171 primary breast tumors of relatively small size and low NPI, and 49 breast cancer cell-lines. Objectives of the study were to study the molecular taxonomy and the genomic aberration patterns in a breast cancer cohort representative of breast cancer demographics. Keywords: array comparative genomic hybridisation

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platform:: GPL5737
220 Samples

Download data: TXT

Series

Accession:: GSE8757

ID:: 200008757

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000754512.

Affymetrix 500K Mapping Array data from breast tumors

(Submitter supplied) Fifty-one breast tumors were profiled for copy-number alterations with the high-resolution Affymetrix 500K Mapping Array. Combined analysis of the prevalence and amplitude of copy-number alterations defined regions of recurrent gain or loss. Gains were most frequently observed on chromosomes 1, 8, 10, 11, 13, 15, 17, and 20. Losses were most frequent on chromosomes 3, 6, 11, 13, 14, 16, and 17. Compared with previous lower-resolution data, our analysis provided significantly more precise boundaries for frequently altered regions, greatly reducing the number of potential alteration-driving genes. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platforms:: GPL3718 GPL3720
102 Samples

Download data: CEL, EXP

Series

Accession:: GSE7545

ID:: 200007545

PubMed Similar studies

Select item 20009717713.

Genome-wide multi-omics profiling reveals extensive genetic complexity in 8p11-p12 amplified breast carcinomas [expression]

(Submitter supplied) Transcriptomic profiling of human breast tumors. Genomic and expression profiling using 38K BAC array-CGH and Illumina HT-12 beadchips were performed on 53 invasive breast tumors to assess the impact of gene dosage on gene expression patterns and the effect of other mechanisms on transcriptional levels. Array-CGH results was validated by FISH using tumors showing 8p11-p12 DNA amplification and expression profiling was confirmed using qPCR for 11 transcripts. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6947
53 Samples

Download data: IDAT, TXT

Series

Accession:: GSE97177

ID:: 200097177

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002048614.

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma

(Submitter supplied) Genomic and expression profiling using 38K BAC array-CGH and Illumina HT-12 beadchips were performed on 97 diploid invasive breast tumors to assess the impact of gene dosage on gene expression patterns and the effect of other mechanisms on transcriptional levels. Patient stratification was performed according to axillary lymph node status (node-negative, pN0; node-positive, pN1) and overall survival (>8-year survivors; breast cancer-specific mortality within 8 years of diagnosis). more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by array

Platforms:: GPL6947 GPL9077
194 Samples

Download data: CSV, GPR, IDAT

Series

Accession:: GSE20486

ID:: 200020486

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002048315.

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma (CGH)

Organism:: Homo sapiens

Type:: Genome variation profiling by array

Platform:: GPL9077
97 Samples

Download data: GPR

Series

Accession:: GSE20483

ID:: 200020483

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002046216.

Clinical implications of gene dosage and gene expression patterns in diploid breast carcinoma (transcriptomic profiling)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6947
97 Samples

Download data: CSV, IDAT, TXT

Series

Accession:: GSE20462

ID:: 200020462

Select item 20000709717.

SCLC cell line profiling on HG-U133A arrays

(Submitter supplied) RNA expression analysis was performed to compare patterns to DNA copy number changes and sensitivity to BCL2 inhibitors. Keywords: cell line comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3029
Platform:: GPL571
34 Samples

Download data: CEL

Series

Accession:: GSE7097

ID:: 200007097

Select item 302918.

Small-cell lung carcinoma cell lines of varying sensitivity to a Bcl-2 antagonist

Analysis of small-cell lung carcinoma cell (SCLC) lines. Expression profiles compared to the cell lines' sensitivity to the Bcl-2 antagonist ABT-737 and chromosomal gains that include changes in Bcl-2 gene copy number. ABT-737 induces the regression of a fraction of SCLC solid tumors.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 4 genotype/variation sets

Platform:: GPL571
Series:: GSE7097
34 Samples

Download data: CEL

DataSet

Accession:: GDS3029

ID:: 3029

Select item 20001087819.

Integrative Genome-wide Analysis of Glioblastoma.

(Submitter supplied) Glioblastoma multiforme shows multiple chromosomal aberrations, the impact of which on gene expression remains unclear. To investigate this relationship and to identify putative initiating genomic events, we integrated a paired copy number and gene expression survey in glioblastoma using whole human genome arrays. Loci of recurrent copy number alterations were combined with gene expression profiles obtained on the same tumor samples. more...