GEO DataSets

(Submitter supplied) Neural crest (NC) cells are a multipotent, highly migratory cell population that generates most of the components of the peripheral nervous system (PNS), including the glial satellite and Schwann cells. In addition, NC cells also gives rise to another type of PNS glial cell, the boundary cap (BC) cells. These latter cells are located at the interface between central nervous system and PNS, at the exit/entry points of ventral motor and dorsal sensory axons. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL7017

8 Samples

Download data: GPR

(Submitter supplied) We used microarrays to test the fundamental quantitative differences between central and peripheral nervous system transcriptomes. Keywords: repeat

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2209

Platform:

GPL1261

6 Samples

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Analysis of spinal cord (SC) and dorsal root ganglion (DRG). The central nervous system (CNS) comprises the brain and SC; the peripheral nervous system (PNS) includes spinal and cranial nerves along with their associated DRGs. Results identify gene expression differences between the CNS and the PNS.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 tissue sets

Platform:

GPL1261

Series:

GSE5425

6 Samples

Download data

(Submitter supplied) The molecular mechanisms controlling stem cell renewal and lineage commitment are still poorly understood due to lack of reliable markers. In the adult small intestine, an example of high rate self-renewing tissue, four different epithelial cell lineages (enterocytes, Goblet, enteroendocrine and Paneth cells) are generated from a pool of stem cells localised at the bottom of the crypts of Lieberkühn. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6943

8 Samples

Download data: GPR

(Submitter supplied) wild-type mouse (FVB strain) expression profiles of adult sciatic nerve and of cultured Schwann cell Keywords: other

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL11

2 Samples

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(Submitter supplied) Cellular diversity of the brain is largely attributed to the spatial and temporal heterogeneity of progenitor cells. In mammalian cerebral development, it has been difficult to determine how neural progenitor cells are heterogeneous, due to their dynamic changes in nuclear position and gene expression. To address this issue, we systematically analyzed the cDNA profiles of a large number of single progenitor cells at the mid-embryonic stage. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

70 Samples

Download data: CEL, CHP

(Submitter supplied) The amino acid homocysteine increases in the serum when there is insufficient folic acid or vitamin B12, or with certain mutations in enzymes important in methionine metabolism. Elevated homocysteine is related to increased risk for cardiovascular and other diseases in adults and elevated maternal homocysteine increases the risk for certain congenital defects, especially those that result from abnormal development of the neural crest and neural tube. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Dataset:

GDS2646

Platform:

GPL3213

6 Samples

Download data: CEL

Analysis of cultured cardiac neural crest cells treated with homocysteine (HC). Elevated maternal HC increases the risk for congenital defects that result from abnormal development of the neural crest and neural tube. Results provide insight into the molecular basis of HC-induced dysmorphogenesis.

Organism:

Gallus gallus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL3213

Series:

GSE6868

6 Samples

Download data: CEL

(Submitter supplied) Expression profiling of mouse embryos at E2.5, E3.5, E4.25, E4.5, E5.5 E6.0 to identify genes regulated during development of the ICM (inner cell mass), TE (Trophectoderm) and PrE (Primative endoderm) Keywords: development

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL519

5 Samples

Download data: GPR

(Submitter supplied) This microarray study aimed at identifying the differences in the global gene expression growth program of adult cultured olfactory ensheathing cells (cOEC) (from the olfactory bulb) versus adult cultured Schwann cells (SC) (from the sciatic nerve) and versus adult OEC directly dissected from the olfactory nerve layer (nOEC). The aim of the comparison between cOEC and SC is to define intrinsic molecular differences that distinguish cOEC from SC (both cell types support neuronal regeneration). more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL890

9 Samples

Download data: TXT

(Submitter supplied) The goal was to determine differentially expressed genes between hEPI-NCSC and Schwann cells generated thereof. RNA was isolated from (a) ex vivo expanded hEPI-NCSC (XP; Clewes O et al, 2011) and from (b) human Schwann cells that were differentiated from hEPI-NCSC (unpublished data)

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

6 Samples

Download data: TXT

(Submitter supplied) Cells were isolated from mouse embryonic neural crest stem cells at culture day 2 (NCSC), from day 7 in vitro differentiated progeny (NCP) and day 2 epidermal neural crest stem cells from bulge explants of adult whisker follicles (EPI-NCSC). Keywords: LongSAGE

Organism:

Mus musculus

Type:

Expression profiling by SAGE

Platform:

GPL1349

3 Samples

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(Submitter supplied) Skin-derived precursors (SKPs) are multipotent dermal stem cells that reside within a hair follicle niche and that share properties with embryonic neural crest precursors. Here, we have asked whether SKPs and their endogenous dermal precursors originate from the neural crest or whether, like the dermis itself, they originate from multiple developmental origins. To do this, we used two different mouse Cre lines that allow us to perform lineage tracing: Wnt1-cre, which targets cells deriving from the neural crest, and Myf5-cre, which targets cells of a somite origin. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL6247

13 Samples

Download data: CEL, CHP

(Submitter supplied) Time course of early development of peripheral nerve, from embryonic day 9.5 to postnatal day 0. Origin of samples: mouse embryos expressing green fluorescent protein (GFP) in neural crest stem cells and later glial cells under the control of the proteolipid protein gene (Plp) promoter. At E9.5 the trunk region was dissected out. At E12, E14, E16, E18 and P0 the sciatic nerve was taken. GFP-expressing cells were isolated by FACS sorting. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS890

Platform:

GPL81

19 Samples

Download data: CEL

Expression profiling of neural crest stem cells at embryonic day (E) 9.5 and developing Schwann cells (SC) at E12, E14, E16, E18, and mature SCs at birth. Cells isolated by FACS from proteolipid-GFP transgenics. Results provide insight into stem cell regulation and Schwann cell development.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 6 age, 3 development stage sets

Platform:

GPL81

Series:

GSE972

19 Samples

Download data: CEL