Similar studies for GEO DataSets (Select 200012790) - GEO DataSets

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Items: 20

Select item 2000127901.

Gene expression profiling of human breast cancers and cancer cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
98 Samples

Download data: CEL

Series

Accession:: GSE12790

ID:: 200012790

Select item 2000293272.

Gene expression profiling of MCF10A (miR-221/222 vs control)

(Submitter supplied) Analysis of gene expression of MCF10A to identify the targets of miR-221 and miR-222 Keywords: MCF10, miR-221, miR-222

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4797
Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE29327

ID:: 200029327

Select item 2000127773.

Gene expression profiling of 51 human breast cancer cell lines

(Submitter supplied) Basal gene expression levels were determined by global gene expression profiling of breast cancer cell lines. Molecular subtype was determined using gene expression and HER2 status assesses by HER2 FISH analysis. Keywords: Basal gene expression (no stimulation or timecourse)

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
51 Samples

Download data: CEL

Series

Accession:: GSE12777

ID:: 200012777

Select item 2000127644.

Gene expression changes upon expression of activated versions of MEK1 and HRAS in MCF10A cells

(Submitter supplied) MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors Cells were lysed 24 hours post-transfection with collection of total RNA and protein Keywords: Oncogene inducation of gene expression changes

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
17 Samples

Download data: CEL

Series

Accession:: GSE12764

ID:: 200012764

Select item 2000127635.

Gene expression profiling of 30 human breast cancers

(Submitter supplied) We used microarrays to profile 30 human primary breast tumors and determine global gene expression patterns and molecular subtypes Keywords: Basal gene expression in human tumor samples

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE12763

ID:: 200012763

Select item 2000108436.

mRNA Cancer Cell Line Profiles

(Submitter supplied) mRNA cancer cell line profiles Keywords: cancer, cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
206 Samples

Download data: CEL

Series

Accession:: GSE10843

ID:: 200010843

Select item 2000108337.

miRNA Cancer Cell Line Profiles

(Submitter supplied) miRNA cancer cell line profiles Keywords: cancer, cell lines

Organism:: Rattus norvegicus; Homo sapiens; Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL5106
409 Samples

Download data: GPR

Series

Accession:: GSE10833

ID:: 200010833

Select item 47978.

MCF10A mammary epithelial cell line transfected with miR-221/222 mimic

Analysis MCF10A cells transfected with synthetic oligo mimics for microRNAs (miRNAs) miR-221 and miR-222. Both miRNAs are abundant in the basal-like subtype of breast cancer but not in the luminal subtype. Results provide insight in to the role of miR-221/222 in the pathogenesis of breast cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL570
Series:: GSE29327
6 Samples

Download data: CEL

DataSet

Accession:: GDS4797

ID:: 4797

Select item 2000192229.

Expression data from TKI258 treated 4T1 cells and 4T1 tumors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
12 Samples

Download data: CEL

Series

Accession:: GSE19222

ID:: 200019222

Select item 20001922110.

Expression data from TKI258 treated 4T1 tumors

(Submitter supplied) 4T1 mouse mammary carcinoma cells have an autocrine FGFR active loop leading to constitutive activation of downstream signaling pathways. We found that FGFR inhibitors have a strong effect on 4T1 tumors in-vivo. We used microarray to understand the contribution of FGFR signaling to the tumor formation upon TKI258 treatment.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
6 Samples

Download data: CEL

Series

Accession:: GSE19221

ID:: 200019221

Select item 20001922011.

Expression data from TKI258 treated 4T1 cells

(Submitter supplied) 4T1 mouse mammary carcinoma cells have an autocrine FGFR active loop leading to constitutive activation of downstream signaling pathways. We found that FGFR inhibitors have a strong effect on the proliferation and survival of these cells. We used microarray to understand the contribution of FGFR signaling to the tumorigenic phenotype of the 4T1 cells.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
6 Samples

Download data: CEL

Series

Accession:: GSE19220

ID:: 200019220

Select item 20002071912.

Gene expression changes upon treatment of T47D breast cancer cells with the Pan-PI3 kinase inhibitor GDC-0941

(Submitter supplied) We sought to determine genes whose expression changed upon treatment with a selective inhibitor of class I PI3 kinase.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE20719

ID:: 200020719

Select item 20003845913.

miRNA profiles in head and neck natural epithelial - mesenchymal phenotype cell line pair, and in TGF-β induced EMT models

(Submitter supplied) Sixth generation Exiqon® locked nucleic acid miRCURY™ LNA microarrays were used to search and validate some unidentified miRNAs that regulate EMT in head and neck cancer carcinoma.

Organism:: Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis

Type:: Non-coding RNA profiling by array

Platform:: GPL11434
3 Samples

Download data: TXT

Series

Accession:: GSE38459

ID:: 200038459

Select item 20007466714.

Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.

(Submitter supplied) Abstract BACKGROUND: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling pathways driving basal-like tumorigenesis are not fully elucidated. METHODS: One hundred sixteen unselected breast tumors were subjected to integrated analysis of phosphoinositide 3-kinase (PI3K) pathway related molecular aberrations by immunohistochemistry, mutation analysis, and gene expression profiling. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
95 Samples

Download data: TXT

Series

Accession:: GSE74667

ID:: 200074667

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004376515.

Expression data from exponentially proliferating ovarian cancer cell lines

(Submitter supplied) We used microarrays to assess gene expression in proliferating ovarian cancer cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
98 Samples

Download data: CEL

Series

Accession:: GSE43765

ID:: 200043765

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002533216.

Restoring miR-200c to aggressive endometrial cancer cell line

(Submitter supplied) Using a mimic miR-200c was restored to an aggressive, Type 2 endometrial cancer cell line, Hec50

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
9 Samples

Download data: CEL

Series

Accession:: GSE25332

ID:: 200025332

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003979317.

Copy number profiling of 92 human lung tumors on Affymetrix 100K SNP arrays

(Submitter supplied) Copy number profiling of 92 human lung tumors on Affymetrix 100K SNP arrays was conducted in order to assess the interaction of common genomic alterations with response to targeted anti-cancer therapeutics. Class 1 phosphatidylinositol 3' kinase (PI3K) plays a major role in cell proliferation and survival in a wide variety of human cancers. Here we investigate biomarker strategies for PI3K pathway inhibitors in non-small-cell lung cancer (NSCLC). more...

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platforms:: GPL2004 GPL2005
184 Samples

Download data: CEL

Series

Accession:: GSE39793

ID:: 200039793

PubMed Similar studies

Select item 20005608918.

Expression profiling of EpH4 mouse mammary epithelial cells overexpressing the AP-1 transcription factor component Fra1

(Submitter supplied) RNA of control mouse mammary epithelial cells (EpH4 control) and corresponding fra1 overexpressing cells (EpH4fra1 cl1 and EpH4fra1 cl2) was hybridized onto an 53MM chip and differentially expressed targets were further analysed. For each sample hybridization was performed in technical triplicate

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL18447
3 Samples

Download data: GPR

Series

Accession:: GSE56089

ID:: 200056089

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000600819.

Human ovarian tumors and normal ovaries

(Submitter supplied) 99 individual ovarian tumors (37 endometrioid, 41 serous, 13 mucinous, and 8 clear cell carcinomas) and 4 individual normal ovary samples, each assayed on an Affymetrix HG_U133A array Keywords: Individual tumor comparisons

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
103 Samples

Download data: CEL

Series

Accession:: GSE6008

ID:: 200006008

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000598720.

Mouse model of Endometrioid Ovarian Adenocarcinomas by conditional inactivation of PTEN and APC genes

(Submitter supplied) Fifty million plaque-forming units of AdCre was injected into the right ovarian bursal cavity of 56- 70 day old female mice. Mice were euthanized 63 days later to obtain ovary tumors and normal ovary tissue. Seven individual ovarian tumors and 4 individual normal ovary samples were each assayed on an Affymetrix Mouse Genome 430 2.0 array. Keywords: Tumor vs normal comparisons