GEO DataSets

(Submitter supplied) Investigation of whole genome gene expression level changes in response to different light conditions of the T. reesei QM9414 deletion strains delta-blr1, delta-blr2 and delta env1 cultivated on 1% microcrystalline cellulose. Perception and proper interpretation of environmental signals is crucial for survival in any natural habitat. Although the biotechnological workhorse Trichoderma reesei (Hypocrea jecorina) is predominantly known for its capability of efficient plant cell wall degradation, recent studies show that it has not lost its evolutionary heritage. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

16 Samples

Download data: CALLS, PAIR

(Submitter supplied) The aim of this study was to evaluate changes in the transcriptome due to the lack of CRE1 in light or darkness.

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

8 Samples

Download data: PAIR

(Submitter supplied) The aim of this study was to evaluate changes in the transcriptome upon growth on different carbon sources in light or darkness.

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

20 Samples

Download data: PAIR

(Submitter supplied) The aim of this study was to evaluate changes in the transcriptome due to the lack of adenylate cyclase in light or darkness. As the cAMP pathway represents an output pathway of heterotrimeric G-protein signaling ACY1 is likely to be important for regulation of enzymes in response to different nutrient conditions. Also, a light dependent effect was found earlier.

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

8 Samples

Download data: PAIR

(Submitter supplied) Light represents an important environmental cue, which exerts considerable influence on the metabolism of fungi. Studies with the biotechnological fungal workhorse Trichoderma reesei (Hypocrea jecorina) have revealed an interconnection between transcriptional regulation of cellulolytic enyzmes and the light response. The filamentous fungus, Neurospora crassa, has been used as a model organism to study light and circadian rhythm biology. more...

Organism:

Neurospora crassa

Type:

Expression profiling by array

Platform:

GPL13956

20 Samples

Download data: GPR

(Submitter supplied) Investigation of whole genome gene expression level changes in response to different light conditions of the T. reesei QM9414 parental strain and the deletion strains delta-phlp1, delta-gnb1 and delta gng1, cultivated on 1 % microcrystalline cellulose. The mutants analyzed in this study are further described in Tisch et al. 2011: Carbohydrate degradation is significantly regulated by light and the phosducin like protein PhLP1 in Trichoderma reesei (Hypocrea jecorina).

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

16 Samples

Download data: CALLS, PAIR

(Submitter supplied) We show that YPR2, a transcription factor associated with the SOR cluster, has functions beyond regulation of this cluster in carbon and secondary metabolism and exerts its major function in darkness. It impacts production of secondary metabolites, particularly of Alamethicin and Orsellinic acid.

Organism:

Trichoderma reesei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18110

8 Samples

Download data: XLSX

(Submitter supplied) Investigation of whole genome gene expression level changes in response to different light conditions of the H. jecorina CBS999.97(MAT1-2) parental strain (W) and the deletion strain delta-env1 (E). These two strains were grown on malt extract agar(Merck) at 25℃ in four different conditions: (1) 24L: constant light illumination (24L); (2) 12L12D: in a 12h light/dark cycle and then 6h light illumination; (3) 12D12L: in a 12h dark/light cycle and then 6h constant darknes; (4) 24D: constant darkness. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

24 Samples

Download data: PAIR

(Submitter supplied) Hemicellulose, the second most abundant plant biomass fraction after cellulose, is widely viewed as a potential feedstock for the production of liquid fuels and other value-added materials. Degradation of hemicellulose by filamentous fungi requires production of many different enzymes, which are induced by biopolymers or its derivatives and regulated mainly at the transcriptional level through transcription factors (TFs). more...

Organism:

Neurospora crassa

Type:

Expression profiling by array

Platform:

GPL14949

23 Samples

Download data: GPR, TXT

(Submitter supplied) We investigated the function of the SNX/H-type regulator of G-protein signaling (RGS) protein RGS4 and found alterations in enzyme regulation, stress response, siderophore production and metabolism of several carbon sources in light and darkness

Organism:

Trichoderma reesei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30923

12 Samples

Download data: CSV, FA, TXT

(Submitter supplied) The aim of this study was to evaluate changes in the transcriptome due to the lack of PKAc1 in light or darkness. As the cAMP pathway represents an output pathway of heterotrimeric G-protein signaling PKAc1 is likely to be important for regulation of enzymes in response to different nutrient conditions. Also, a light dependent effect was found earlier.

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

8 Samples

Download data: PAIR

(Submitter supplied) The aim of this study was to evaluate changes in the transcriptome in the mentioned strains upon growth on cellulose

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platforms:

GPL10642 GPL16051

10 Samples

Download data: PAIR, TXT

(Submitter supplied) The asexual spore or conidium plays a critical role in the life cycle of many filamentous fungi, being the primary means for dispersion in the environment. To investigate the transcriptional changes taking place during the sporulation phase in T. reesei, which culminates with the production of the conidiospores, microarray experiments were performed. Among the 1,994 distinct genes displaying >90 % confidence , a total of 900 were classified as differentially expressed, relative to time zero of sporulation, at at least one of the time points analyzed. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

4 Samples

Download data: PAIR, TXT

(Submitter supplied) The ascomycete Trichoderma reesei is one of the most well studied cellulolytic fungi and widely used in the biotechnology industry, as in the production of second-generation bioethanol. Carbon catabolite repression (CCR) mechanism adopted by T. reesei is mediated by the transcription factor CRE1 and consists in the repression of genes related to the production of cellulase when a readily available carbon source is present in the medium. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18110

6 Samples

Download data: TXT

(Submitter supplied) The filamentous fungus Trichoderma reesei is a saprophyte involved with polysaccharides cell wall depolymerization, being the most important industrial source of cellulases, which have been used for bioethanol production. The regulation of cellulase expression is controlled at the transcriptional level and in a carbon source-dependent manner. However, the signaling pathways and mechanisms involved in regulating the expression of these enzymes in T. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22157

27 Samples

Download data: CSV, TXT

(Submitter supplied) Transcriptional profiling with next-generation sequencing methods refined our understanding of the N. crassa transcriptional response to cellulose and demonstrated that the newly characterized transcription factors clr-1 and clr-2 were required for the bulk of that response including induction all major cellulase and some major hemicellulase genes.

Organism:

Neurospora crassa OR74A

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL15146 GPL15147

26 Samples

Download data: TXT

(Submitter supplied) The mitosporic fungus Trichoderma reesei is an industrial producer of enzymes for degradation of lignocellulosic polysaccharides to soluble monomers that can be fermented to biofuels. The genes encoding these enzymes in T. reesei have recently been shown to be clustered in the genome. Here we will show that the expression of these genes is epigenetically controlled at the heterochromatin level by the protein methyltransferase LAE1. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

8 Samples

Download data: CALLS, PAIR, TXT

(Submitter supplied) The ascomycete Trichoderma reesei is an industrial producer of cellulolytic and hemicellulolytic enzymes and also serves as a model for investigations on these enzymes and their genes. Most of them are obligatorily dependent on the Zn(II)Cys(VI) transcriptional activator XYR1. XYR1 is constitutively expressed at a low basal, but induced in the presence of cellulase- and hemicellulose inducers, and transported into the nucleus. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18977

12 Samples

Download data: TSV

(Submitter supplied) Filamentous fungi are one of the primary degraders of plant biomass because of their ability to produce enzymes that break down complex polysaccharides. The production of cellulolytic enzymes in fungi is dependent on transcription factors. In this article, we identified a N. crassa Zn2Cys6 transcription factor Clr5 that regulates the expression of cellulase on cellulose. N. crassa Δclr5 exhibited a significant decrease in secreted proteins (~46%), endo-glucanase (~55%), xylanase (~33%), β-glucosidase (~38%), and exocellulase (~40%) compared with the WT, while transcriptomic analysis revealed that clr5 was essential in cellulase expression. more...

Organism:

Neurospora crassa

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16164

12 Samples

Download data: XLSX

(Submitter supplied) Lactose (1,4-0-ß-d-galactopyranosyl-d-glucose), a by-product from cheese manufacture or whey processing industries, is known to induce the formation of plant biomass hydrolyzing enzymes needed for the biorefinery industry in the fungus Trichoderma reesei, but the reason for this induction and the underlying mechanism are not fully understood. Here, we used systems analysis of the Trichoderma reesei transcriptome during utilization of lactose. more...

Organism:

Trichoderma reesei

Type:

Expression profiling by array

Platform:

GPL10642

6 Samples

Download data: PAIR, TXT