GEO DataSets

(Submitter supplied) Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at Station Recherches Avicoles, Institut National de la Recherche Agronomique Nouzilly, France were used to profile abdominal fat gene expression at 7 weeks of age. The fat line (FL) and lean line (LL) chickens differ in various phenotypic and metabolic measurements, including abdominal fatness, plasma glycemia and triiodothyronine (T3). more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16133

24 Samples

Download data: TXT

(Submitter supplied) Chickens divergently selected for either high growth (HG genotype) or low growth (LG genotype) at SRA-INRA, France were used to profile abdominal adipose gene expression at 7 wk of age. The HG and LG chickens are different in various phenotypic and metabolic measurements, including growth rate, abdominal fat, plasma glycemia, insulinemia, T4, T3, triglyceride and NEFA. The HG and LG chickens are valuable as a model for biomedical and agricultural traits. more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16133

16 Samples

Download data: DIFF, TXT

(Submitter supplied) Chickens divergently selected for either high growth (HG genotype) or low growth (LG genotype) by F.H. Ricard at SRA-INRA, Nouzilly France were used for time-course transcriptional profiling of abdominal fat during juvenile development (1 to 11 weeks of age) to identify differentially expressed genes. The HG and LG chickens are different in various phenotypic and metabolic measurements, including growth rate, abdominal fat, plasma glycemia, insulinemia, T4, T3, triglyceride and NEFA. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

24 Samples

Download data: GPR

(Submitter supplied) Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at SRA-INRA, France were used to profile hepatic gene expression during juvenile development (1 to 11 weeks of age) and to identify differentially expressed genes associated with genotype and age. The fat line (FL) and lean line (LL) chickens are different in various phenotypic and metabolic measurements, including abdominal fatness, plasma glycemia and T3. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

24 Samples

Download data: GPR

(Submitter supplied) Several processes governing growth and metabolism are regulated by the neuroendocrine system, particularly the trophic hormones produced in the anterior pituitary gland. However, many of the differences that exist in pituitary gene expression and functional gene networks associated with divergent growth characteristics are still largely unknown. Using the Del-Mar 14K Chicken Integrated Systems microarray, this experiment evaluated global gene expression in the anterior pituitary gland during the first 7 weeks of post-hatch growth in two lines of chickens genetically selected for high growth (HG) or low growth (LG) at SRA-INRA, France. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

31 Samples

Download data: TXT

(Submitter supplied) Excessive accumulation of lipids in the adipose tissue is a major problem in the present-day broiler industry. However, few studies have analyzed the expression of adipose tissue genes that are involved in pathways and mechanisms leading to adiposity in chickens. Gene expression profiling of chicken adipose tissue could provide key information about the ontogenesis of fatness and clarify the molecular mechanisms underlying obesity. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL3213

10 Samples

Download data: CEL, EXP

(Submitter supplied) Fourty RNA samples from the liver of lean and fat line chickens were organized in 10 pools, 4 by 4 and in the order of chicken adiposity. Expression in these pools were compared Keywords: animals with different genetic background comparison

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL3265

28 Samples

Download data

(Submitter supplied) Hypothalami from Fat (FL) and Lean lines (LL) of juvenile broiler chickens were obtained by divergent selection for high or low levels of abdominal fat at SRA-INRA, France. Gene expression patterns were measured during the development of adiposity at 1 to 7 weeks of age. Differentially expressed genes associated with line, age, or line-by-age were identified. Various phenotypic and metabolic alterations are present between the lines (i.e., abdominal fat, T3 levels and glycemia), however there are no alterations in ad libitum food intake between the lines. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

8 Samples

Download data: TXT

(Submitter supplied) We performed gene expression profiling on chicken livers at five important embryonic developmental stages (E7, E12, E14, E17 and E21), which were selected from chicken lines with significant differences in abdominal fat content. Each developmental stage had its unique gene expression pattern and stage-specific differentially expressed genes (DEGs). Furthermore, the three rapid growth periods (E12, E14 and E17) had similar expression patterns. more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL10223

10 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling in peritoneal adipose tissue of 48 pigs (132 days of age) originated from two lines divergently selected for residual feed intake (RFI) : low-RFI pigs (RFIneg), high-RFI pigs (RFIpl). Both lines were offered isocaloric and isoproteic diets with contrasted energy source and nutrients: low fat, low fiber (LF) diet or a high fat, high fiber (HF)diet during 10 weeks. Effects of RFI selection, diet and interaction between diet and line were investigated.

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL16524

48 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling in subcutaneous adipose tissue of 48 pigs aged (132 days of age) originated from two lines divergently selected for residual feed intake (RFI) : low-RFI pigs (RFIneg), high-RFI pigs (RFIpl). Both lines were offered isocaloric and isoproteic diets with contrasted energy source and nutrients: low fat, low fiber (LF) diet or a high fat, high fiber (HF)diet during 10 weeks. Effects of RFI selection, diet and interaction between diet and line were investigated.

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL16524

48 Samples

Download data: TXT

(Submitter supplied) To investigate genes involved in abdominal fat deposition and fat metabolism of broilers with dw gene, we used highthroughput sequencing to detect the differentially expressed genes in livers and abdominal fats of dwarf broilers which were fed with a normal diet and a high-fat diet, respectively. The broilers began to fed with a normal or a high-fat diet in 1-week-old. After 7 weeks, the broilers were be executed and the livers and abdominal fats were used to extracted total RNAs. more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24996

12 Samples

Download data: TXT

(Submitter supplied) Maternal obesity is linked with increased adverse outcomes for mother and fetus. However, the metabolic impact of excessive fat accumulation within the altered hormonal context of pregnancy is not well understood. We used a murine model of obesity, the high fat diet-fed C57BL/6J mouse to determine adipose tissue-mediated molecular mechanisms driving metabolic dysfunction throughout pregnancy. Remarkably, obese mice exhibited a normalization of visceral fat accumulation at late-stage pregnancy (-53%, P<0.001 E18.5) to achieve levels comparable in mass (per gram of body weight) to that of non pregnant, control diet fed mice. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

20 Samples

Download data: CEL

(Submitter supplied) Domestic chicken has been intensively studied because of its role as an efficient source of lean meat. However, commercial broilers resulting from genetic selection for rapid growth demonstrate detrimental traits, such as excess deposition of abdominal adipose tissue, metabolic disorders, and reduced reproduction. Therefore fast-growing broilers represent “obese” chickens compared to slow-growing egg layers (e.g, Leghorn) or wild strain of meat-type chickens (e.g., Fayoumi). more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL3213

17 Samples

Download data: CEL

(Submitter supplied) Context: It is not known whether biological differences reported between subcutaneous (SAT) and visceral (VAT) adipose tissue depots underlie the pathogenicity of visceral fat. Objective: We compared SAT and VAT gene expression according to obesity, visceral fat accumulation, insulin resistance and presence of the metabolic syndrome. Design: Subjects were assigned into 4 groups (lean, overweight, obese and obese with metabolic syndrome). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

64 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL19630

178 Samples

Download data: TXT

(Submitter supplied) The aim of this study was to evaluate the responses of meat-type chicken to changes in dietary energy sources by comparing high-fiber high-fat vs. standard high-starch diets and using a transcriptomic approach in three major metabolic tissues - liver, adipose tissue and muscle - as well as in circulating blood cells.

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL19630

42 Samples

Download data: TXT

(Submitter supplied) The aim of this study was to evaluate the responses of meat-type chicken to changes in dietary energy sources by comparing high-fiber high-fat vs. standard high-starch diets and using a transcriptomic approach in three major metabolic tissues - liver, adipose tissue and muscle - as well as in circulating blood cells.

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL19630

45 Samples

Download data: TXT

(Submitter supplied) The aim of this study was to evaluate the responses of meat-type chicken to changes in dietary energy sources by comparing high-fiber high-fat vs. standard high-starch diets and using a transcriptomic approach in three major metabolic tissues - liver, adipose tissue and muscle - as well as in circulating blood cells.

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL19630

45 Samples

Download data: TXT

(Submitter supplied) The aim of this study was to evaluate the responses of meat-type chicken to changes in dietary energy sources by comparing high-fiber high-fat vs. standard high-starch diets and using a transcriptomic approach in three major metabolic tissues - liver, adipose tissue and muscle - as well as in circulating blood cells.

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL19630

46 Samples

Download data: TXT