GEO DataSets

(Submitter supplied) S. aureus has the propensity to survive a range of NaCl challenge conditions We used commercially available Affymetrix S. aureus GeneChips (part number 900514) to compare the gene expression properties of wild type cells during growth at no or high (2M) NaCl.

Organism:

Staphylococcus aureus; Staphylococcus aureus subsp. aureus USA300

Type:

Expression profiling by array

Platform:

GPL1339

4 Samples

Download data: CEL, CHP

(Submitter supplied) Investigation of mRNA expression level changes in a Staphylococcus aureus Mu50 delta-SAV1322 mutant, compared to the wild-type strain. A comparison of the wild-type and the mutant transcription profiles

Organism:

Staphylococcus aureus subsp. aureus Mu50

Type:

Expression profiling by array

Platform:

GPL22334

8 Samples

Download data: PAIR

(Submitter supplied) Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Berberine chloride (BBR), a natural plant product, has potent antimicrobial activity against S. aureus. We employed Affymetrix Staphylococcus aureus GeneChipsTM arrays to investigate the global transcriptional profiling of Staphylococcus aureus ATCC25923 treated with berberine chloride. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Dataset:

GDS2814

Platform:

GPL1339

6 Samples

Download data: CEL

Analysis of Staphylococcus aureus ATCC25923 cultures treated with berberine chloride. Results provide insight into the antimicrobial activity of berberine chloride against Staphylococcus aureus.

Organism:

Staphylococcus aureus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL1339

Series:

GSE7944

6 Samples

Download data: CEL

(Submitter supplied) Two excessive NaCl concentrations (0.25% and 1.5%) and two periods of treatment (7 min and 45 min) were used as moderate- and high-salt sress conditions at early and later stages of response, respectively. As a baseline, samples from cells grown on a standard SIS medium in the same growing system and same illumination were used. Keywords: time course and dose response

Organism:

Cereibacter sphaeroides 2.4.1

Type:

Expression profiling by array

Platform:

GPL162

15 Samples

Download data: CEL

(Submitter supplied) Daptomycin is a lipopeptide antibiotic that has recently been approved for treatment of Gram-positive bacterial infections. The mode of action of daptomycin is not yet entirely clear. To further understand the mechanism transcriptomic analysis of changes in gene expression in daptomycin-treated Staphylococcus aureus was carried out. The expression profile indicated that cell wall stress stimulon member genes (B. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Platform:

GPL6059

6 Samples

Download data: TXT

(Submitter supplied) Genome-wide transcriptional profiling studies of the growth of bacteria with antimicrobial agents often reveals aspects of the drug-specific protective bacterial response. Fusidic acid is a steroid antimicrobial that inhibits protein synthesis by interfering with the release of elongation factor G (EF-G) after it has functioned in the translocation step. Two hundred and seventy two genes were both up- and down-regulated in a fusidic acid-susceptible strain of Staphylococcus aureus following challenge with 2 mg/L-1 fusidic acid for 15 min. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Platform:

GPL7072

4 Samples

Download data: TAV

(Submitter supplied) Purpose: To understand how D654Y mutated RpoB affect gene expression under either normal or osmotic stress conditions in Escherichia coli . Methods: RNA-seq libraries were constructed for four samples, including (I) The parental strain Suc-T110 grown at normal condition (5%w/v glucose); (II)RpoB mutant RpoBD645Y [Suc-T110::rpoB (D654Y), RNA-seq library named NZ-502] grown at normal condition;(III) Suc-T110 grown at osmotic stress condition(12%w/v glucose);(IV) NZ-502 grown at osmotic stress condition. more...

Organism:

Escherichia coli ATCC 8739

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22139

4 Samples

Download data: TXT

(Submitter supplied) Two single-gene knockout strains (ΔfapR and Δcra) and their common parent strain (JWCB005) were each grown in three conditions of elevated osmolarity which produced a moderate growth defect in all strains and relative growth phenotypes between the strains.

Organism:

Caldicellulosiruptor bescii

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23843

27 Samples

Download data: XLSX