Similar studies for GEO DataSets (Select 200074741) - GEO DataSets

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Items: 20

Select item 2000747411.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL16192 GPL6503
12 Samples

Download data: SGR, TXT

Series

Accession:: GSE74741

ID:: 200074741

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000747402.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [ChIP-chip]

(Submitter supplied) Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast. Occupancy profiling of Red1, Mtl1, and Mmi1 proteins in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
10 Samples

Download data: TXT

Series

Accession:: GSE74740

ID:: 200074740

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000747393.

A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [sRNA-seq]

(Submitter supplied) Co-transcriptional RNA processing and surveillance factors mediate heterochromatin formation in fission yeast. In addition to RNAi, RNA elimination machinery including MTREC (Mtl1-Red1 core) and the exosome are involved in facultative heterochromatin assembly, however, the exact mechanisms remain unclear. Here we show that RNA elimination factors cooperate with the conserved exoribonuclease Dhp1/Rat1/Xrn2, which couples pre-mRNA 3’-end processing to transcription termination, to promote premature termination and facultative heterochromatin formation at meiotic genes. more...

Organism:: Schizosaccharomyces pombe

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16192
2 Samples

Download data: SGR

Series

Accession:: GSE74739

ID:: 200074739

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000772914.

A NOVEL EPIGENETIC SILENCING PATHWAY INVOLVING the HIGHLY CONSERVED 5'-3' EXORIBONUCLEASE Dhp1/Rat1/Xrn2 in SCHIZOSACCHAROMYCES POMBE

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by array; Other

Platforms:: GPL19654 GPL13988
8 Samples

Download data: BEDGRAPH, BIGWIG, TXT

Series

Accession:: GSE77291

ID:: 200077291

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000772905.

A NOVEL EPIGENETIC SILENCING PATHWAY INVOLVING the HIGHLY CONSERVED 5'-3' EXORIBONUCLEASE Dhp1/Rat1/Xrn2 in SCHIZOSACCHAROMYCES POMBE [CRAC-seq]

(Submitter supplied) Epigenetic gene silencing plays a critical role in regulating gene expression and contributes to organismal development and cell fate acquisition in eukaryotes. In fission yeast, Schizosaccharomyces pombe, heterochromatin-associated gene silencing is known to be mediated by RNA processing pathways including RNA interference (RNAi) and a 3’-5’ exoribonuclease complex exosome. Here, we report a new RNA-processing pathway that contributes to epigenetic gene silencing and assembly of heterochromatin mediated by 5’-3’ exoribonuclease Dhp1/Xrn2. more...

Organism:: Schizosaccharomyces pombe

Type:: Other

Platform:: GPL13988
5 Samples

Download data: BIGWIG

Series

Accession:: GSE77290

ID:: 200077290

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000772896.

A NOVEL EPIGENETIC SILENCING PATHWAY INVOLVING the HIGHLY CONSERVED 5'-3' EXORIBONUCLEASE Dhp1/Rat1/Xrn2 in SCHIZOSACCHAROMYCES POMBE [gene expression]

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by array

Platform:: GPL19654
3 Samples

Download data: BEDGRAPH, TXT

Series

Accession:: GSE77289

ID:: 200077289

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001231447.

CPF is required for heterochromatin assembly and gene silencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL16192
23 Samples

Download data: BEDGRAPH, BW, TXT

Series

Accession:: GSE123144

ID:: 200123144

PubMed Full text in PMC Similar studies

Select item 2001231388.

CPF is required for heterochromatin assembly and gene silencing [RNA-seq]

(Submitter supplied) RNA sequencing in Schizosaccharomyces pombe

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20584
4 Samples

Download data: TXT

Series

Accession:: GSE123138

ID:: 200123138

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001231379.

CPF is required for heterochromatin assembly and gene silencing [ChIP-seq]

(Submitter supplied) Mapping of H3K9me2, 3' RNA processing and termination factors, and terminating RNA polymerase II in Schizosaccharomyces pombe

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20584 GPL16192
19 Samples

Download data: BEDGRAPH, BW

Series

Accession:: GSE123137

ID:: 200123137

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20007611410.

Expression profiling and ChIP-chip of Schizosaccharomyces pombe strains wildtype, erh1∆, and ccr4∆

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL6503 GPL16192
21 Samples

Download data: FPKM_TRACKING, TXT

Series

Accession:: GSE76114

ID:: 200076114

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007611211.

Expression profiling of fission yeast strains: wild-type, erh1∆, and ccr4∆

(Submitter supplied) We report gene expression profiling in the fission yeast Schizosaccharomyces pombe. We performed high-throughput sequencing of RNA isolated from wild-type, erh1∆, and ccr4∆ strains. We find that many meiotic gene containing degradation sequence DSR are expressed in vegetative erh1∆, while these meiotic mRNAs do not increase in ccr4∆, indicating that Erh1 and Ccr4 target different set of genes during vegetative growth.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16192
5 Samples

Download data: FPKM_TRACKING

Series

Accession:: GSE76112

ID:: 200076112

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20007611112.

The fission yeast Schizosaccharomyces pombe: H3K9me2, Erh1-GFP and CFP-Mmi1 ChIP-chip

(Submitter supplied) ChIP-chip analyses of H3K9me2 (in WT, erh1∆, mmi1∆ and ccr4∆), Erh1-GFP (in WT and mmi1∆) and CFP-Mmi1 (in WT)

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
16 Samples

Download data: TXT

Series

Accession:: GSE76111

ID:: 200076111

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003340413.

RNA elimination machinery targeting meiotic mRNAs promotes facultative heterochromatin formation

(Submitter supplied) Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
5 Samples

Download data: TXT

Series

Accession:: GSE33404

ID:: 200033404

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007882314.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
22 Samples

Download data: TXT

Series

Accession:: GSE78823

ID:: 200078823

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007882215.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [Taz1]

(Submitter supplied) Occupancy profiling of Shelterin components in fission yeast. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
4 Samples

Download data: TXT

Series

Accession:: GSE78822

ID:: 200078822

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007882116.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [Rec12]

(Submitter supplied) Occupancy profiling of Rec12 during fission yeast meiosis. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
1 Sample

Download data: TXT

Series

Accession:: GSE78821

ID:: 200078821

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007882017.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [H3K9me2]

(Submitter supplied) ChIP-chip analyses of lysine 9 dimethylated histone H3 in Shelterin mutants. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6503
6 Samples

Download data: TXT

Series

Accession:: GSE78820

ID:: 200078820

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007881918.

Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins [BrdU]

(Submitter supplied) BrdU profiling of replication activity in hydroxyurea treated synchronous culture of fission yeast. Facultative heterochromatin regulates gene expression, but its assembly is poorly understood. Previously, we identified facultative heterochromatin islands in the fission yeast genome and found that RNA elimination machinery promotes island assembly at meiotic genes. Here, we report that Taz1, a component of the telomere protection complex Shelterin, is required to assemble heterochromatin islands at regions corresponding to late replication origins that are sites of double-strand break formation during meiosis. more...