Similar studies for GEO DataSets (Select 200085058) - GEO DataSets

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Items: 20

Select item 2000850581.

Identification and profiling of microRNAs in two developmental stages of the model cestode parasite Mesocestoides corti

(Submitter supplied) MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in fundamental biological processes such as metabolism and development. The particular developmental characteristics of cestode parasites highlight the importance of studying miRNA gene regulation in these organisms. Here, we performed a comprehensive analysis of miRNAs in two developmental stages of the model cestode Mesocestoides corti. more...

Organism:: Mesocestoides corti

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL22262
6 Samples

Download data: TXT

Series

Accession:: GSE85058

ID:: 200085058

PubMed Similar studies SRA Run Selector

Select item 2000647052.

microRNA profiling in the zoonotic parasite Echinococcus canadensis using a high-throughput approach

(Submitter supplied) microRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in fundamental biological processes such as development and metabolism. Here, we perform a comprehensive analysis of miRNAs in the zoonotic parasite E. canadensis G7, one of the causative agents of the neglected disease cystic echinococcosis. Small RNA libraries from protoscoleces and cyst walls of E. more...

Organism:: Echinococcus canadensis; Echinococcus granulosus

Type:: Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL18185 GPL19605
6 Samples

Download data: TXT

Series

Accession:: GSE64705

ID:: 200064705

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Select item 2000631453.

HITS–CLIP reveals Argonaute 1-associated MicroRNAs and Target Sites in Schistosoma japonicum

(Submitter supplied) In this study, we isolated and identified the small RNAs associated with the S. japonicum Argonaute protein, SjAgo1, by HITS-CLIP combined with bioinformatic analysis. These data reveal a genome-wide miRNA-mRNA interaction map in S. japonicum in vivo, which will help us understand the complex gene regulation network in this pathogen and thereby facilitate to develop novel approaches against Schistosomiasis.

Organism:: Schistosoma japonicum

Type:: Other

Platform:: GPL11650
1 Sample

Download data: FA, TXT

Series

Accession:: GSE63145

ID:: 200063145

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Select item 2000541804.

Genome-wide sequencing of small RNAs of Echinococcus granulosus shows microRNAs may be involved life cycle stage development and differentiation

(Submitter supplied) MicroRNAs (miRNAs) are important post-transcriptional regulators which control growth and development in eukaryotic animals. The cestode Echinococcus granulosus has a complex life-cycle involving different development stages but the mechanisms underpinning this development, including the involvement of miRNAs, remain unknown. Using Illumina deep-sequencing technology, we sequenced at the genome-wide level three small RNA populations from the adult, protoscolex and cyst membrane of E. more...

Organism:: Echinococcus granulosus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL18185
3 Samples

Download data: TXT

Series

Accession:: GSE54180

ID:: 200054180

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000414025.

microRNAs in C. elegans, P. pacificus, and S. ratti: Conserved miRNAs are candidate post-transcriptional regulators of developmental arrest in free-living and parasitic nematodes

(Submitter supplied) Animal development is complex yet surprisingly robust. Animals may develop alternative phenotypes conditional on environmental changes. Under unfavorable conditions C. elegans larvae enter the dauer stage, a developmentally arrested, long-lived, and stress-resistant state. Dauer larvae of free-living nematodes and infective larvae of parasitic nematodes share many traits including a conserved endocrine signaling module (DA/DAF-12), which is essential for the formation of dauer and infective larvae. more...

Organism:: Pristionchus pacificus; Caenorhabditis elegans; Strongyloides ratti

Type:: Non-coding RNA profiling by high throughput sequencing

7 related Platforms
10 Samples

Download data: TXT

Series

Accession:: GSE41402

ID:: 200041402

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Select item 2000831896.

PyMT 4 stages tumor progression microRNA sequencing

(Submitter supplied) We sequenced mammary gland samples of MMTV-PyMT mouse from 4 stages (hyperplasia at week 6, adenoma/MIN at week 8, early carcinoma at week 10, and late carcinoma with lung metastasis at week 12) during tumor progression.

Organism:: Mus musculus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL17021
24 Samples

Download data: CSV

Series

Accession:: GSE83189

ID:: 200083189

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Select item 2000310097.

miRNA of Pacific oyster Crassostrea gigas for different organs and developmental stages

(Submitter supplied) miRNA sequencing of Pacific oyster Crassostrea gigas for different organs and developmental stages.

Organism:: Magallana gigas

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL13986
21 Samples

Download data: BEDGRAPH

Series

Accession:: GSE31009

ID:: 200031009

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Select item 2000277138.

Genome-wide analysis of gene expression patterns in mir-122 knockout mice livers

(Submitter supplied) To invesigate the physiology roles of mir-122 in liver, we performed expression profiling of mir-122 knockout mice and the control B6/129 mice.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
7 Samples

Download data: CEL, CHP

Series

Accession:: GSE27713

ID:: 200027713

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000725949.

Identification of miRNAs and its targets using high-throughput sequencing and degradome analysis in male and female Asparagus officinalis.

(Submitter supplied) Two independent small RNA (sRNA) libraries from male and female asparagus plants were sequenced, generating 4.13 and 5.88 million final cleaned reads, respectively. A total of 154 conserved miRNA belonging to 26 families, and 40 novel miRNA candidates that seemed to be specific to asparagus were identified, among them, 63 miRNAs exhibited significant differential expression between male and female plants, and 36 target mRNAs representing 44 conserved and fournovel miRNA in asparagus by high-throughput degradome sequencing analysis.

Organism:: Asparagus officinalis

Type:: Non-coding RNA profiling by high throughput sequencing; Other

Platform:: GPL20875
3 Samples

Download data: XLS

Series

Accession:: GSE72594

ID:: 200072594

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Select item 20009256510.

High depth sequencing of BrU-labeled nascent RNA.

(Submitter supplied) BrU incorporation into nascent RNA followed by immunoprecipitation with a BrU specific antibody. The nascent RNA was subsequently eluted with BrU competition.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
4 Samples

Download data: BW

Series

Accession:: GSE92565

ID:: 200092565

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20005686211.

Genome-wide quantification of microRNA processing efficiency from RNA-seq data

(Submitter supplied) Microprocessor is responsible for conversion of pri-miRNA transcripts into pre-miRNA hairpins in miRNA biogenesis. The in vivo properties of this process remain enigmatic. Here, we present the first study of in vivo transcriptome-wide pri-miRNA processing using next-generation sequencing of chromatin-associated pri-miRNAs. We identify a distinctive Microprocessor signature in the transcriptome profile, from which efficiency of the endogenous processing event can be accurately quantified. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16791
12 Samples

Download data: TXT

Series

Accession:: GSE56862

ID:: 200056862

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20002224412.

miRNA expression profile analysis of Clonorchis sinensis by Solexa deep sequencing

(Submitter supplied) Clonorchis sinensis is a zoonotic parasite causing clonorchiasis associated with human diseases such as biliary calculi, cholecystitis, liver cirrhosis, and is classified as carcinogenic to humans for cholangiocarcinoma. MicroRNAs (miRNAs) are non-coding, regulating small RNA molecules essential for the complex life cycle of parasites and involved in parasitic infections. To identify and characterize miRNAs expressed in adult C. more...

Organism:: Clonorchis sinensis

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL10530
1 Sample

Download data: TXT

Series

Accession:: GSE22244

ID:: 200022244

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20003564713.

High-throughput sequencing of small RNAs from adult Taenia multiceps

(Submitter supplied) sRNA profiling from adult Taenia multiceps by Illumina high-throughput sequencing was used to increase our understanding of the molecular regulation mechanisms of the cestode,find novel biomarkers for the parasitic disease and search new strategies to control these parasites.

Organism:: Taenia multiceps

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL15209
1 Sample

Download data: TXT

Series

Accession:: GSE35647

ID:: 200035647

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Select item 20012441714.

Identifying microRNAs and their editing sites in Macaca mulatta

(Submitter supplied) MicroRNAs are small non-coding RNAs that are critical in post-transcriptional regulation. According to the latest miRBase (v22), there are 617 annotated pre-miRNAs in Macaca mulatta, which is much less than 1917 in human, although both of these two species are primates. To improve the annotation of miRNAs in Macaca mulatta, we generated 12 small RNA profiles from 8 tissues and perform comprehensive analysis of these profiles. more...

Organism:: Macaca mulatta

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL14954
12 Samples

Download data: TXT

Series

Accession:: GSE124417

ID:: 200124417

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Select item 20002990415.

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity (normal prostate and prostate cells)

(Submitter supplied) Modification of microRNA sequences by the 3' addition of nucleotides to generate so-called isomiR adds to the complexity of miRNA function, with recent reports showing that 3' modifications can influence miRNA stability and efficiency of target repression. Here we show that the 3' modification of miRNAs is a physiological and common post-transcriptional event that shows selectivity for specific miRNAs and is observed across species ranging from C. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL10400 GPL9052
3 Samples

Download data: FA

Series

Accession:: GSE29904

ID:: 200029904

PubMed Full text in PMC Similar studies

Select item 20002697016.

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Other; Non-coding RNA profiling by high throughput sequencing

5 related Platforms
107 Samples

Download data: FA, RCC

Series

Accession:: GSE26970

ID:: 200026970

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002691917.

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity (Validation 2)

(Submitter supplied) Modification of microRNA sequences by the 3' addition of nucleotides to generate so-called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3' modifications can influence miRNA stability and efficiency of target repression. Here we show that the 3' modification of miRNAs is a physiological and common post-transcriptional event that shows selectivity for specific miRNAs and is observed across species ranging from C. more...