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LSD1 inhibitor T-3775440 inhibits SCLC cell proliferation by disrupting LSD1 interactions with SNAG domain proteins INSM1 and GFI1B
PubMed Similar studies Analyze with GEO2R
A novel LSD1 inhibitor T-3775440 induces transdifferentiation in AML cell lines
A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC
A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (ChIP-Seq)
PubMed Similar studies SRA Run Selector
A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (BeadChip)
A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (microarray)
Small cell lung cancer PDX model response to LSD1 inhibitor RG6016/ORY1001
PubMed Full text in PMC Similar studies
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001
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Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001
Gene expression from H69M versus H69 SCLC cell lines
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq]
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [ChIP-Seq]
PubMed Full text in PMC Similar studies SRA Run Selector
Effects of loss of LSD1 activity on small cell lung cancer cell lines via pharmacological inhibition
PubMed Full text in PMC Similar studies Analyze with GEO2R
RNA expression in MDA-MB-231 cells transfected with scramble, LSD1 or HDAC5 shRNA (HG-U133A_2)
Transcriptomic changes induced by GFI1B variants
GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation
Inhibition of LSD1 with bomedemstat sensitizes small cell lung cancer to immune checkpoint blockade and T cell killing
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811.
Effects of LSD1 inhibitors on enhancer functions in T-ALL cells
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