Similar studies for GEO DataSets (Select 200121555) - GEO DataSets

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Items: 3

Select item 2001215551.

RNASeq analysis of untreated versus treated

(Submitter supplied) We report differential regulated genes in three pathogenic bacterial strains after treatment with a new antimicrobial.

Organism:: Staphylococcus aureus; Streptococcus pyogenes; Enterococcus faecium

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL23589 GPL19006 GPL20656
18 Samples

Download data: XLSX

Series

Accession:: GSE121555

ID:: 200121555

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001755352.

RNAseq transcriptome analysis of A. baumannnii MS14413 treated with PBT2, zinc and tetracycline

(Submitter supplied) Acinetobacter baumannii causes high mortality in ventilator-associated pneumonia patients and antibiotic treatment is compromised in multi-drug resistant strains resistant to beta-lactams, carbapenems, cephalosporins, polymyxins and tetracyclines. Among COVID-19 patients receiving ventilator support, multi-drug resistant A. baumannii secondary infection is associated with a two-fold increase in mortality. more...

Organism:: Acinetobacter baumannii

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24655
12 Samples

Download data: XLSX

Series

Accession:: GSE175535

ID:: 200175535

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001599013.

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

(Submitter supplied) This study reports on the co-administration of a zinc ionophore (PBT-2) and ampicillin to break antibiotic resistance of Streptococcus pneumoniae in a murine pneumonia model. The molecular mechanism for this heightened antimicrobial activity was identified through transcriptomic and metabolomic analyses of a wild type strain and a zinc efflux mutant to identify cellular targets of zinc intoxication. more...