GEO DataSets

(Submitter supplied) This series consists of gene expression microarray data from non-Hodgkin lymphoma tumors for which we have performed targeted DNA sequencing with the 380 gene LymphoSeq panel.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

290 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), as well as activated B-cell-like (ABC) and germinal center B-cell-like (GCB) molecular subtypes of DLBCL. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

17 Samples

Download data: CEL, TXT

(Submitter supplied) Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), as well as activated B-cell-like (ABC) and germinal center B-cell-like (GCB) molecular subtypes of DLBCL. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4221

Platform:

GPL570

17 Samples

Download data: CEL, TXT

Analysis of tumors from HIV+ male patients with AIDS-related lymphomas (ARL). HIV+ individuals have an increased risk of developing an aggressive B-cell Non-Hodgkin Lymphoma relative to HIV- persons. Results identify a signature for ARL subtypes and provide insight into pathogenetic events in ARL.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state, 2 genotype/variation, 4 other, 11 tissue sets

Platform:

GPL570

Series:

GSE17189

17 Samples

Download data: CEL

(Submitter supplied) Primary mediastinal large B-cell lymphoma (PMBL) represents a clinically and pathologically distinct subtype of large B-cell lymphomas. Furthermore, molecular studies, including global gene expression profiling, have provided evidence that PMBL is more closely related to classical Hodgkin lymphoma (cHL). Although targeted sequencing studies have revealed a number of mutations involved in PMBL pathogenesis, a comprehensive description of disease-associated genetic alterations and perturbed pathways is still lacking. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL14951

120 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Third-party reanalysis

Platform:

GPL6246

6 Samples

Download data: CEL

(Submitter supplied) Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary B-NHL samples, identifying high HDAC9 expression among various lymphoma entities and HDAC9 copy number gains in 50% of diffuse large B-cell lymphoma (DLBCL). more...

Organism:

Mus musculus

Type:

Expression profiling by array; Third-party reanalysis

Download data: TXT

(Submitter supplied) Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary B-NHL samples, identifying high HDAC9 expression among various lymphoma entities and HDAC9 copy number gains in 50% of diffuse large B-cell lymphoma (DLBCL). more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6246

6 Samples

Download data: CEL