Similar studies for GEO DataSets (Select 200202656) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from GEO DataSets

Items: 3

Select item 2002026561.

Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion

(Submitter supplied) Candida glabrata is a human-associated opportunistic fungal pathogen. It shares its niche with Lactobacillus spp. in the gastrointestinal and vaginal tract. In fact, Lactobacillus species are thought to competitively prevent Candida overgrowth. We investigated the molecular aspects of this antifungal effect by analyzing the interaction of C. glabrata strains with Limosilactobacillus fermentum. From a collection of clinical C. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25492
22 Samples

Download data: CSV

Series

Accession:: GSE202656

ID:: 200202656

PubMed Full text in PMC Similar studies

Select item 2001911452.

Loss-of-function ROX1 mutations suppress the fluconazole susceptibility of upc2A∆ mutation in Candida glabrata, implicating additional positive regulators of ergosterol biosynthesis

(Submitter supplied) Two of the major classes of antifungal drugs in clinical use target ergosterol biosynthesis. Despite its importance, our understanding of the transcriptional regulation of ergosterol biosynthesis genes in pathogenic fungi is essentially limited to the role of hypoxia and sterol-stress induced transcription factors such as Upc2 and Upc2A as well as homologs of Sterol Response Element Binding (SREB) factors. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL31108
25 Samples

Download data: XLSX

Series

Accession:: GSE191145

ID:: 200191145

PubMed Full text in PMC Similar studies

Select item 2000649763.

An antifungal benzimidazol reveals novel sterols after inhibition of Erg11.

(Submitter supplied) Fungal infections are a serious health problem in clinics especially in the immune-compromised patient. Disease ranges from widespread superficial infections like vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses only a limited arsenal of antifungals is available. The most commonly used classes of antifungal compounds used include azoles, polyenes and echinocandines. more...