Similar studies for GEO DataSets (Select 200225174) - GEO DataSets

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Items: 2

Select item 2002251741.

Next Generation Sequencing Facilitates Quantitative Analysis of DLBCL Cell Line SU-DHL-4 Cells with P2X7 Receptor Signaling Activation or Inhibition

(Submitter supplied) The goals of this study aim to reveal the role of P2X7 receptor signaling in DLBCL

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
3 Samples

Download data: TXT

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Accession:: GSE225174

ID:: 200225174

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001181462.

Expression data of ex vivo purified CD4+ cells from WT and P2rx7-/- mice

(Submitter supplied) Extracellular adenosine triphosphate (eATP) is a signaling molecule that affects T cell function via the ionotropic P2X7 receptor. The study of effector/memory T cells isolated from mice with deletion of P2rx7, the gene encoding for P2X7, allowed understanding the impact of P2X7 activity on T cell function in the eATP-rich tumor microenvironment. To explore the the transcriptional impact of the lack of P2rx7 in CD4+ naïve and TEM cells, we performed genome-wide expression profiling of ex vivo purified CD4+ naïve and TEM cells from WT and P2rx7-/- mice