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Full record GDS4886

Histone deacetylase 3 deficiency effect on the heart

Analysis of hearts of 6 week old mutants deleted for histone deacetylase 3 (HDAC3). HDAC3 deletion occurred 7 days after birth. These MCH3-KO mutants are viable on normal chow but a high fat diet is lethal. The results underscore the impact gene-diet interactions may have on cardiovascular health.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL6246
Series:
GSE31251
8 Samples
Download data: CEL

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