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Full record GDS4361

AP1510, TGFα or heregulin ligand effect on MCF10 mammary epithelial cells expressing HER2-FKBP-HA chimeric receptors

Analysis of mammary epithelial MCF10A/HER2/FKBP/HA cells treated with AP1510 to induce the chimeric HER2-FKBP molecule to homodimerize, or with TGFα or heregulin to induce heterodimerization with EGFR or HER3. Results provide insight into signaling events following HER2 receptor dimerization.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 agent sets
Platform:
GPL6244
Series:
GSE22288
12 Samples
Download data: CEL, CHP

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