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Single-oocyte transcriptome analysis reveals aging-associated effects influenced by life stage and calorie restriction

(Submitter supplied) Chromosome segregation errors in oocytes lead to the production of aneuploid eggs, which are the leading cause of pregnancy loss and of several congenital diseases such as Down syndrome. The frequency of chromosome segregation errors in oocytes increases with maternal age, especially at a late stage of reproductive life. How aging at various life stages affects oocytes differently remains poorly understood. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
401 Samples
Download data: TXT
Series
Accession:
GSE159281
ID:
200159281

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