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Items: 1 to 20 of 303

1.

Genomic and transcriptomic analyses reveal insights into cadmium resistance mechanisms of Cupriavidus nantongensis E324

(Submitter supplied) The cadmium-resistant Cupriavidus sp. E324 strain has been previously shown to have a high potential for use in cadmium (Cd) remediation, due to its high capacity for cadmium bioaccumulation. According to the comparative genomic analysis, the E324 strain was most closely related to C. nantongensis X1 T , indicating that the E324 strain should be re-identified as C. nantongensis. To unravel the Cd tolerance mechanisms of C. more...
Organism:
Cupriavidus nantongensis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34734
6 Samples
Download data: TXT
Series
Accession:
GSE272856
ID:
200272856
2.

Effects of metals on the gene expression of Cupriavidus basilensis SRS

(Submitter supplied) To investigate the molecular mechanisms of how Cupriavidus basilensis SRS may aid bioextraction of metals from ores, we exposed C. basilensis SRS to different metals, as well as natural ores
Organism:
Cupriavidus basilensis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32789
10 Samples
Download data: TXT
Series
Accession:
GSE216827
ID:
200216827
3.

Response of efflux system deletion mutants of Cupriavidus metallidurans to Zn and EDTA

(Submitter supplied) Response of Cupriavidus metallidurans AE104 and 2 deletion mutants to Zn and EDTA
Organism:
Cupriavidus metallidurans; Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
27 Samples
Download data: TXT
Series
Accession:
GSE181790
ID:
200181790
4.

Adaptation of Cupriavidus metallidurans CH34 to toxic zinc concentrations involves an uncharacterized ABC-type transporter

(Submitter supplied) Cupriavidus metallidurans CH34 is a well-studied metal-resistant β-proteobacterium and contains a battery of genes involved in the resistance and processing of numerous metals. Here, we performed a directed evolution experiment to obtain derivatives adapted to grow in the presence of zinc at concentrations above the minimal inhibitory concentration for the parental strain. Genetic characterization of one derivative, CH34ZnR, which was also more resistant to cadmium, revealed seven mutations, including inactivation of glpR coding for a DeoR-type transcriptional repressor by insertion of IS1088. more...
Organism:
Cupriavidus metallidurans CH34; Cupriavidus metallidurans
Type:
Expression profiling by array
Platform:
GPL4980
3 Samples
Download data: GPR
Series
Accession:
GSE156826
ID:
200156826
5.

Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator

(Submitter supplied) These data belong to a metabolic engineering project that introduces the reductive glycine pathway for formate assimilation in Cupriavidus necator. As part of this project we performed short-term evolution of the bacterium Cupriavidus necator H16 to grow on glycine as sole carbon and energy source. Some mutations in a putiative glycine transporting systems facilitated growth, and we performed transcriptomics on the evolved strain growing on glycine. more...
Organism:
Cupriavidus necator
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27909
3 Samples
Download data: TAB
Series
Accession:
GSE151887
ID:
200151887
6.

Elucidating photorespiration pathways in a chemolithoautotroph

(Submitter supplied) We investigate photorespiration pathways in the chemoautotroph Cupriavidus necator H16 when growing autotropically on hydrogen and carbon dioxide via the Calvin Cycle. We demonstrate an upregulation of the glycerate pathway under photorespiration (ambient carbon dioxide) conditions
Organism:
Cupriavidus necator
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27909
6 Samples
Download data: TAB
Series
Accession:
GSE141999
ID:
200141999
7.

Spontaneous mutation in the AgrRS two-component regulatory system of Cupriavidus metallidurans results in enhanced silver resistance via a novel mechanism involving nanoparticle formation

(Submitter supplied) Background: The uncontrolled and widespread use of (nano)silver compounds has led to the increased release of these compounds into the environment, raising concerns about their negative impact on ecosystems. Concomitantly, silver resistance determinants are widely spread among environmental and clinically relevant bacteria although the underlying mechanisms are not yet fully understood. Results: In this study, we show that Cupriavidus metallidurans is able to adapt to toxic silver concentrations and explicate the genetic circuit responsible for this adaptation. more...
Organism:
Cupriavidus metallidurans; Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL4980
18 Samples
Download data: GPR
Series
Accession:
GSE107669
ID:
200107669
8.

Response of ECF sigma factor deletion mutants of Cupriavidus metallidurans to mixed metal ions (Co, Cu, Cd, Zn, Ni, 30 µM each)

(Submitter supplied) Response of Cupriavidus metallidurans CH34 and ECF deletion mutants to mixed metals
Organism:
Cupriavidus metallidurans CH34; Cupriavidus metallidurans
Type:
Expression profiling by array
Platform:
GPL16115
16 Samples
Download data: TXT
Series
Accession:
GSE115771
ID:
200115771
9.

Influence of AE104(∆zur) mutant of Cupriavidus metallidurans on Zn stress

(Submitter supplied) Response of Cupriavidus metallidurans AE104 and delta zur mutant to Zn stress
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
9 Samples
Download data: TXT
Series
Accession:
GSE98926
ID:
200098926
10.

Zinc-Induced Transposition of Insertion Sequence Elements Contributes to Increased Adaptability of Cupriavidus metallidurans

(Submitter supplied) Bacteria can respond to adverse environments by increasing their genomic variability and subsequently facilitating adaptive evolution. To demonstrate this, the contribution of Insertion Sequence (IS) elements to the genetic adaptation of Cupriavidus metallidurans AE126 to toxic zinc concentrations was determined. This derivative of type strain CH34, devoid of its main zinc resistance determinant, is still able to increase its zinc resistance level. more...
Organism:
Cupriavidus metallidurans CH34; Cupriavidus metallidurans
Type:
Expression profiling by genome tiling array
Platform:
GPL4980
9 Samples
Download data: GPR
Series
Accession:
GSE74091
ID:
200074091
11.

Response of Cupriavidus metallidurans CH34 to different Pt-species

(Submitter supplied) Response of Cupriavidus metallidurans CH34 to cisplatin, Pt(IV)chloride and Au-NP
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
7 Samples
Download data: TXT
Series
Accession:
GSE78723
ID:
200078723
12.

Integrative analysis of the biodegradation of acetone/isopropanol by Cupriavidus metallidurans CH34: proposal of a metabolic pathway

(Submitter supplied) Various environmental bacteria were adapted to the presence of toxic and recalcitrant organic solvents. Cupriavidus metallidurans CH34, a β-proteobacterium that was found in industrial environments is known as a bacterial model to study heavy metal resistance. Interestingly, genome screening of CH34 also reveals the existence of genes involved in the degradation of recalcitrant organic solvents, such acetone and aromatic compounds. more...
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL4980
3 Samples
Download data: GPR
Series
Accession:
GSE33578
ID:
200033578
13.

Stress response of Cupriavidus metallidurans strains (AE104 delta 7)

(Submitter supplied) Response of Cupriavidus metallidurans AE104(delta zupT) mutant to Zn/EDTA stress
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
6 Samples
Download data: TXT
Series
Accession:
GSE71011
ID:
200071011
14.

Stress response of Cupriavidus metallidurans strains

(Submitter supplied) Response of Cupriavidus metallidurans CH34, AE104 and delta zupT mutant to Zn/EDTA stress
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
16 Samples
Download data: TXT
Series
Accession:
GSE64196
ID:
200064196
15.

Metal resistant bacterium Cupriavidus metallidurans CH34

(Submitter supplied) Metal resistant bacterium Cupriavidus metallidurans CH34 uses non-conventional proteins to combat oxidative stress Keywords: Cupriavidus metallidurans; hydrogen peroxide; oxidative stress;
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL4980
3 Samples
Download data: GPR
Series
Accession:
GSE24094
ID:
200024094
16.

RNA-seq analysis of polyhydroxyalkanoate-producing Ralstonia eutropha H16

(Submitter supplied) Ralstonia eutropha H16 is well-known to produce poly(3-hydroxybutyrate) [P(3HB)], a kind of polyhydroxyalkanoates attracted as bio-based biodegradable plastics, efficiently as an energy storage material under unbalanced growth conditions. To obtain further extended knowledge of PHA biosynthesis, this study employed quantitative transcriptome analysis based on deep sequencing of complementary DNA generated from RNA (RNA-seq) for R. more...
Organism:
Cupriavidus necator H16
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17263
3 Samples
Download data: TXT
Series
Accession:
GSE47759
ID:
200047759
17.

Variation in genomic islands contribute to genome plasticity in Cupriavidus metallidurans

(Submitter supplied) Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter is well-studied for its resistance to a wide range of metals, which is carried for a substantial part by its two megaplasmids pMOL28 and pMOL30. Comparative genomic hybridization (CGH) indicated that the extensive arsenal of determinants involved in metal resistance was well conserved among the different C. more...
Organism:
Cupriavidus metallidurans; Cupriavidus metallidurans CH34
Type:
Genome variation profiling by genome tiling array
Platform:
GPL4980
15 Samples
Download data: GPR
Series
Accession:
GSE36303
ID:
200036303
18.

Response of Cupriavidus metallidurans CH34 to different Au-species

(Submitter supplied) Response of Cupriavidus metallidurans CH34 to NaAuCl4, Au(I)-thiomalate, Au(I)-thiosulfate, KAuCN, (KCN as control)
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL16115
24 Samples
Download data: TXT
Series
Accession:
GSE42199
ID:
200042199
19.

Reliable analysis of the catabolic gene landscape and transcriptome for pollutant degradation using a custom open source microarray with internal calibration

(Submitter supplied) Despite various efforts to develop tools to detect and compare the activity and catabolic potential and activity for pollutant degradation of microorganisms in environmental samples, an open-source, curated and reliable method is still required. Here we report on a customize normalization system that can be applied to any microarray design, allowing the assessment of reliability of signals and enabling cross-experiment comparisons. more...
Organism:
Paraburkholderia xenovorans LB400; Cupriavidus pinatubonensis JMP134; unidentified microorganism; Pseudomonas putida F1; Rhizorhabdus wittichii RW1
Type:
Expression profiling by array
Platform:
GPL13771
23 Samples
Download data: TXT
Series
Accession:
GSE30303
ID:
200030303
20.

Cellular Response of the bacterium Cupriavidus metallidurans CH34 to Strontium: bio-precipitation as strontium carbonate.

(Submitter supplied) The physiological and transcriptomic response of the metal resistant bacterium Cupriavidus metallidurans strain CH34 in response to stable (non-radioactive) strontium ions (Sr) was investigated. C. metallidurans CH34 could survive and proliferate in the presence of relatively high concentrations of SrCl2 (D10 is 70mM, MIC is 120 mM). Precipitation of Sr as strontium carbonate was observed in the culture during aerobic growth of CH34 in the presence of 60 mM SrCl2. more...
Organism:
Cupriavidus metallidurans CH34
Type:
Expression profiling by array
Platform:
GPL4980
9 Samples
Download data: GPR
Series
Accession:
GSE29863
ID:
200029863
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