GEO DataSets

(Submitter supplied) Burkholderia cepacia complex bacteria comprise opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. These microorganisms produce exopolysaccharides which are considered virulence determinants. Here, we report the isolation of an evolved nonmucoid variant (17616nmv) after the ancestor, Burkholderia multivorans ATCC 17616, was subjected to prolonged stationary phase. more...

Organism:

Burkholderia multivorans; Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616

Type:

Expression profiling by array

Platform:

GPL13356

6 Samples

Download data: CEL

(Submitter supplied) The LitR/CarH protein family is a adenosyl B12 (AdoB12)-dependent photoreceptor with DNA-binding activity and its homologs are widely distributed in the genome of diverged bacterial genera. Here, we studied a role and function of a LitR homolog from a Gram-negative soil bacteria Burkholderia multivorans, which has no AdoB12-binding domain. Transcriptome analysis revealed the existence of 19 light-induced genes (folE, cfa, litS, a Photolyase gene phrB2, cryB2) located in the flanking region of litR. more...

Organism:

Burkholderia multivorans; Burkholderia multivorans ATCC 17616

Type:

Expression profiling by array

Platform:

GPL24783

4 Samples

Download data: PAIR

(Submitter supplied) Burkholderia multivorans comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation including the mucoid-to-nonmucoid colony morphotype. Here we studied three Burkholderia multivorans clonal isolates (mucoid D2095 (BM11L), and nonmucoid D2214G and D2214P) and a laboratory nonmucoid variant (BM11L-nmv1) obtained under prolonged stationary phase. more...

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616

Type:

Expression profiling by array

Platform:

GPL13356

12 Samples

Download data: CEL

(Submitter supplied) Within this work we identified and characterized gene Bmul_2557 (ldhR) of B. multivorans ATCC 17616, a bacterial species associated with chronic respiratory infections in cystic fibrosis patients. LdhR belongs to the LysR-type family of transcriptional regulators and its deletion from the B. multivorans genome affected considerably the formation of planktonic cellular aggregates and surface-attached biofilms.

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616

Type:

Expression profiling by array

Platform:

GPL13356

9 Samples

Download data: CEL

(Submitter supplied) Hfq proteins are RNA chaperones that play a critical role in post-transcription regulation of gene expression. Bacteria of the Burkholderia cepacia complex harbor two distinct and functional Hfq proteins, the Hfq and Hfq2. We have previously performed the functional analysis of Hfq and Hfq2 in the pathogen Burkholderia cenocepacia J2315. In order to examine the impacts of each RNA chaperone on the global transcriptome of B. more...

Organism:

Burkholderia cenocepacia; Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616

Type:

Expression profiling by array

Platform:

GPL13356

9 Samples

Download data: CEL, TXT

(Submitter supplied) The bacterial tyrosine (BY) kinase family comprises the major group of bacterial enzymes endowed with tyrosine kinase activity. We have previously shown that the BceF protein from Burkholderia cepacia IST408 belongs to this BY kinase family and is involved in the biosynthesis of the exopolysaccharide cepacian. However, little is known about the extent of regulation in the cell by this kinase protein. more...

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616; Burkholderia cepacia

Type:

Expression profiling by array

Platform:

GPL15600

10 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Burkholderia multivorans; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315

Type:

Expression profiling by array; Other

Platform:

GPL13356

10 Samples

Download data: CEL

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection. more...

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616

Type:

Other

Platform:

GPL13356

4 Samples

Download data: CEL, TXT

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection.

Organism:

Burkholderia multivorans; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315

Type:

Expression profiling by array

Platform:

GPL13356

6 Samples

Download data: CEL

(Submitter supplied) NimbleGen design name 110225_RDKK301_Bmul_expr. A 1:2 expression design for 5,981 genes from Burkholderia multivorans ATCC17616 with six 60-mer probe pairs (PM/MM) per gene. Each probe is replicated 2 times. The design includes random GC and other control probes. Protocol: High-density DNA array prepared with Maskless Array Synthesizer (MAS) technology. See manufacturer's website at http://www.nimblegen.com/.

Organism:

Burkholderia multivorans ATCC 17616

1 Series

4 Samples

Download data: NDF, NGD

(Submitter supplied) This array is identical to GPL13356, but a custom CDF environment is used to extract data. DNA-based probe-selection was performed using Xspecies DNA hyb CDF batchmaker v3.2, available here: http://affymetrix.arabidopsis.info/xspecies/. An optimal signal cutoff of 80 and minimum number of probes per probe set of 7 were determined empirically, resulting in the masking of 24223 of the original 226576 probes on the array and the exclusion of 156 probe sets. more...

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616

1 Series

1 Related Platform

10 Samples

Download data: CDF, TXT

(Submitter supplied) see manufacturer's web site The parameters chosen for the custom array design were as follows: 11-micron feature size, standard 12.8-mm array format, prokaryotic antisense target type, perfect-match probes only, full length sequence for probe selection, and eight as the minimum acceptable probes per sequence.

Organism:

Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616

7 Series

1 Related Platform

46 Samples

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