U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prkn parkin RBR E3 ubiquitin protein ligase [ Mastomys coucha (southern multimammate mouse) ]

Gene ID: 116076805, updated on 18-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Prkn
Gene description
parkin RBR E3 ubiquitin protein ligase
See related
EnsemblRapid:ENSMCUG00000004633
Gene type
protein coding
RefSeq status
MODEL
Organism
Mastomys coucha
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mastomys
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Prkn in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current UCSF_Mcou_1 (GCF_008632895.1) Unplaced Scaffold NW_022196911.1 (9168755..10407405, complement)

NW_022196911.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform pseudogene Neighboring gene uncharacterized LOC116078967 Neighboring gene U7 small nuclear RNA Neighboring gene arginine/serine-rich coiled-coil protein 2-like Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene 60S ribosomal protein L19-like Neighboring gene uncharacterized LOC116076810 Neighboring gene parkin coregulated Neighboring gene uncharacterized LOC116076809 Neighboring gene QKI, KH domain containing RNA binding

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_022196911 Unplaced Scaffold Reference UCSF_Mcou_1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin conjugating enzyme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
E3 ubiquitin-protein ligase parkin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Mastomys coucha Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCSF_Mcou_1 Primary Assembly

Genomic

  1. NW_022196911.1 Reference UCSF_Mcou_1 Primary Assembly

    Range
    9168755..10407405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031350750.1 → XP_031206610.1  E3 ubiquitin-protein ligase parkin isoform X2

    Conserved Domains (5) summary
    smart00647
    Location:312 → 374
    IBR; In Between Ring fingers
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam01485
    Location:412 → 452
    IBR; IBR domain, a half RING-finger domain
    pfam17976
    Location:144 → 216
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:227 → 317
    zf-RING_14; RING/Ubox like zinc-binding domain

  2. XM_031350749.1 → XP_031206609.1  E3 ubiquitin-protein ligase parkin isoform X1

    Related
    ENSMCUP00000005295.1, ENSMCUT00000006708.1
    Conserved Domains (5) summary
    smart00647
    Location:313 → 375
    IBR; In Between Ring fingers
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam01485
    Location:413 → 453
    IBR; IBR domain, a half RING-finger domain
    pfam17976
    Location:145 → 217
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:228 → 318
    zf-RING_14; RING/Ubox like zinc-binding domain

  3. XM_031350751.1 → XP_031206611.1  E3 ubiquitin-protein ligase parkin isoform X3

    Conserved Domains (5) summary
    smart00647
    Location:311 → 373
    IBR; In Between Ring fingers
    cd01798
    Location:2 → 74
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam01485
    Location:411 → 451
    IBR; IBR domain, a half RING-finger domain
    pfam17976
    Location:143 → 215
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:226 → 316
    zf-RING_14; RING/Ubox like zinc-binding domain

  4. XM_031350752.1 → XP_031206612.1  E3 ubiquitin-protein ligase parkin isoform X4

    Conserved Domains (4) summary
    smart00647
    Location:313 → 375
    IBR; In Between Ring fingers
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam17976
    Location:145 → 217
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:228 → 318
    zf-RING_14; RING/Ubox like zinc-binding domain

  5. XM_031350754.1 → XP_031206614.1  E3 ubiquitin-protein ligase parkin isoform X6

  6. XM_031350753.1 → XP_031206613.1  E3 ubiquitin-protein ligase parkin isoform X5

    Conserved Domains (3) summary
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam17976
    Location:145 → 217
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:228 → 290
    zf-RING_14; RING/Ubox like zinc-binding domain

  7. XM_031350756.1 → XP_031206616.1  E3 ubiquitin-protein ligase parkin isoform X8

    Conserved Domains (3) summary
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam17976
    Location:145 → 217
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:228 → 246
    zf-RING_14; RING/Ubox like zinc-binding domain

  8. XM_031350755.1 → XP_031206615.1  E3 ubiquitin-protein ligase parkin isoform X7

    Conserved Domains (3) summary
    cd01798
    Location:3 → 76
    Ubl_parkin; ubiquitin-like (Ubl) domain found in parkin and similar proteins
    pfam17976
    Location:145 → 217
    zf-RING_12; RING/Ubox like zinc-binding domain
    pfam17978
    Location:228 → 245
    zf-RING_14; RING/Ubox like zinc-binding domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases