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Taf9b TATA-box binding protein associated factor 9b [ Rattus norvegicus (Norway rat) ]

Gene ID: 171152, updated on 4-Jan-2025

Summary

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Official Symbol
Taf9bprovided by RGD
Official Full Name
TATA-box binding protein associated factor 9bprovided by RGD
Primary source
RGD:621116
See related
EnsemblRapid:ENSRNOG00000061102 AllianceGenome:RGD:621116
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dn7; Taf9l; TAFII31
Summary
Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in programmed cell death and response to organic cyclic compound. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex and transcription factor TFTC complex. Orthologous to human TAF9B (TATA-box binding protein associated factor 9b). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 126.6), Thymus (RPKM 87.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Taf9b in Genome Data Viewer
Location:
Xq22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (75354823..75366166, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (71289290..71300142, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (77281234..77295238, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L19, pseudogene 17 Neighboring gene phosphoglycerate kinase 1 Neighboring gene 40S ribosomal protein S21-like Neighboring gene fibronectin type III domain containing protein 3C1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole. Stierum R, et al. Food Chem Toxicol, 2008 Aug. PMID 18539377
  2. Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF. Aoki T, et al. Biochem Biophys Res Commun, 1997 May 8. PMID 9168994
  3. In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. Chen Z, et al. J Biol Chem, 2003 Sep 12. PMID 12837753
  4. TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. Frontini M, et al. Mol Cell Biol, 2005 Jun. PMID 15899866, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cell growth ISO
Inferred from Sequence Orthology
more info
  
involved_in programmed cell death IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFTC complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transcription initiation factor TFIID subunit 9B
Names
DN-7
TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kD
TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor
neuronal cell death-related gene in neuron 7
transcription-associated factor TAFII31L
NP_598299.2
XP_006257055.3
XP_006257056.3
XP_038955366.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133615.2 → NP_598299.2  transcription initiation factor TFIID subunit 9B

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/Swiss-Prot
    Q5EAN8, Q62880
    UniProtKB/TrEMBL
    A6IV45
    Conserved Domains (1) summary
    pfam02291
    Location:5 → 125
    TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    75354823..75366166 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006256994.5 → XP_006257056.3  transcription initiation factor TFIID subunit 9B isoform X1

    UniProtKB/TrEMBL
    A0A0G2K6Z1
    Related
    ENSRNOP00000073996.2, ENSRNOT00000090833.3

  2. XM_006256993.5 → XP_006257055.3  transcription initiation factor TFIID subunit 9B isoform X3

  3. XM_039099438.2 → XP_038955366.2  transcription initiation factor TFIID subunit 9B isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q62880.2 GenPept UniProtKB/Swiss-Prot:Q62880

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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