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C18C4.7 GRIP domain-containing protein;Golgin-84 [ Caenorhabditis elegans ]

Gene ID: 178941, updated on 4-Jan-2025

Summary

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Official Symbol
C18C4.7
Official Full Name
GRIP domain-containing protein;Golgin-84
Primary source
WormBase:WBGene00015968
Locus tag
CELE_C18C4.7
See related
AllianceGenome:WB:WBGene00015968
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See C18C4.7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
23
Sequence:
Chromosome: V; NC_003283.11 (5550314..5567219, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Cystic Fibrosis Transmembrane conductance regulator homolog Neighboring gene Putative UDP-glucuronosyltransferase ugt-48 Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Globin-like protein 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microfilament motor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of myosin II complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in myosin filament IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in myosin filament IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GRIP domain-containing protein;Golgin-84
NP_001343821.1
  • Confirmed by transcript evidence
NP_001343823.1
  • Confirmed by transcript evidence
NP_001359878.1
  • Partially confirmed by transcript evidence
NP_001380227.1
  • Confirmed by transcript evidence
NP_741539.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5550314..5567219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373024.2 → NP_001359878.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MNV5
    Conserved Domains (2) summary
    COG1196
    Location:187 → 959
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:5 → 279
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. NM_001356643.3 → NP_001343821.1  Golgin-84 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2C9C3A0
    Conserved Domains (1) summary
    cl25732
    Location:573 → 1286
    SMC_N; RecF/RecN/SMC N terminal domain

  3. NM_001392515.1 → NP_001380227.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2C9C3R1
    Conserved Domains (2) summary
    COG1196
    Location:319 → 1116
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:97 → 341
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  4. NM_171458.7 → NP_741539.2  GRIP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741539.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYV8
    Conserved Domains (2) summary
    COG1196
    Location:187 → 984
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cl19219
    Location:17 → 101
    DUF342; Protein of unknown function (DUF342)

  5. NM_001356645.5 → NP_001343823.1  GRIP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2C9C3J8
    Conserved Domains (1) summary
    cl25732
    Location:293 → 1090
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
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