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sec-16A.2 Protein transport protein sec16 [ Caenorhabditis elegans ]

Gene ID: 181084, updated on 4-Jan-2025

Summary

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Official Symbol
sec-16A.2
Official Full Name
Protein transport protein sec16
Primary source
WormBase:WBGene00017419
Locus tag
CELE_F13B9.1
See related
AllianceGenome:WB:WBGene00017419
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in Golgi organization and protein localization to endoplasmic reticulum exit site. Predicted to be located in Golgi membrane and endoplasmic reticulum. Predicted to be active in ER to Golgi transport vesicle membrane and endoplasmic reticulum exit site. Orthologous to several human genes including SEC16A (SEC16 homolog A, endoplasmic reticulum export factor). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sec-16A.2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
16
Sequence:
Chromosome: X; NC_003284.9 (8287249..8294519)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ground-like domain-containing protein Neighboring gene Mediator of RNA polymerase II transcription subunit 27 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
  2. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  3. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  4. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  5. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in COPII vesicle coating IEA
Inferred from Electronic Annotation
more info
  
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization to endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in ER to Golgi transport vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum exit site IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein transport protein sec16
NP_001024557.1
  • Partially confirmed by transcript evidence
NP_001360731.1
  • Partially confirmed by transcript evidence
NP_001360732.1
  • Confirmed by transcript evidence
NP_001360733.1
  • Confirmed by transcript evidence
NP_509399.2
  • Confirmed by transcript evidence
NP_509400.3
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    8287249..8294519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373387.3 → NP_001360731.1  Protein transport protein sec16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IM30
    Conserved Domains (3) summary
    cd09233
    Location:903 → 1258
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
    PRK10263
    Location:1328 → 1459
    PRK10263; DNA translocase FtsK; Provisional
    pfam09507
    Location:230 → 438
    CDC27; DNA polymerase subunit Cdc27

  2. NM_076999.9 → NP_509400.3  Protein transport protein sec16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509400.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZQ8
    Conserved Domains (1) summary
    cd09233
    Location:925 → 1280
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

  3. NM_001029386.5 → NP_001024557.1  Protein transport protein sec16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024557.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZQ9
    Conserved Domains (1) summary
    cd09233
    Location:903 → 1258
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

  4. NM_076998.5 → NP_509399.2  Protein transport protein sec16 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509399.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95ZV3
    Conserved Domains (1) summary
    cd09233
    Location:903 → 1258
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

  5. NM_001373388.2 → NP_001360732.1  Protein transport protein sec16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKE4
    Conserved Domains (4) summary
    cd09233
    Location:862 → 1217
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
    PHA03247
    Location:1353 → 1568
    PHA03247; large tegument protein UL36; Provisional
    PRK10263
    Location:1287 → 1418
    PRK10263; DNA translocase FtsK; Provisional
    pfam04747
    Location:206 → 398
    DUF612; Protein of unknown function, DUF612

  6. NM_001373389.3 → NP_001360733.1  Protein transport protein sec16 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IKA6
    Conserved Domains (3) summary
    cd09233
    Location:862 → 1217
    ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
    PRK10263
    Location:1287 → 1418
    PRK10263; DNA translocase FtsK; Provisional
    pfam04747
    Location:206 → 398
    DUF612; Protein of unknown function, DUF612
Nucleotide Protein
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