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Proser2 proline and serine rich 2 [ Mus musculus (house mouse) ]

Gene ID: 227545, updated on 27-Nov-2024

Summary

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Official Symbol
Proser2provided by MGI
Official Full Name
proline and serine rich 2provided by MGI
Primary source
MGI:MGI:2442238
See related
Ensembl:ENSMUSG00000045319 AllianceGenome:MGI:2442238
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5430407P10Rik
Summary
Is expressed in several structures, including alimentary system; cranial ganglion; cranium; sensory organ; and submandibular gland primordium. Orthologous to human PROSER2 (proline and serine rich 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in stomach adult (RPKM 13.4), liver adult (RPKM 5.9) and 20 other tissues See more
Orthologs
human all
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Genomic context

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See Proser2 in Genome Data Viewer
Location:
2 A1; 2 3.62 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (6103304..6135100, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (6098493..6130291, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03581 Neighboring gene UPF2 regulator of nonsense transcripts homolog (yeast) Neighboring gene STARR-seq mESC enhancer starr_03584 Neighboring gene STARR-seq mESC enhancer starr_03586 Neighboring gene predicted gene, 30136 Neighboring gene TRAF-interacting protein pseudogene Neighboring gene predicted gene 10857 Neighboring gene STARR-seq mESC enhancer starr_03588 Neighboring gene RIKEN cDNA A230108P19 gene Neighboring gene enoyl Coenzyme A hydratase domain containing 3 Neighboring gene predicted gene, 54100

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Ye Q, et al. Development, 2022 Aug 15. PMID 35831953, Free PMC Article
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

General gene information

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Markers

Homology

Clone Names

  • MGC36947

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
proline and serine-rich protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159657.2 → NP_001153129.1  proline and serine-rich protein 2

    See identical proteins and their annotated locations for NP_001153129.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    AL928735
    Consensus CDS
    CCDS15671.1
    UniProtKB/Swiss-Prot
    Q3V1L9, Q8C5R2, Q8R017, Q8R2Z9
    Related
    ENSMUSP00000060780.6, ENSMUST00000054254.12
    Conserved Domains (2) summary
    PHA03247
    Location:97 → 261
    PHA03247; large tegument protein UL36; Provisional
    pfam15385
    Location:439 → 469
    SARG; Specifically androgen-regulated gene protein

  2. NM_144883.5 → NP_659132.2  proline and serine-rich protein 2

    See identical proteins and their annotated locations for NP_659132.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    AL928735
    Consensus CDS
    CCDS15671.1
    UniProtKB/Swiss-Prot
    Q3V1L9, Q8C5R2, Q8R017, Q8R2Z9
    Related
    ENSMUSP00000110592.3, ENSMUST00000114942.9
    Conserved Domains (2) summary
    PHA03247
    Location:97 → 261
    PHA03247; large tegument protein UL36; Provisional
    pfam15385
    Location:439 → 469
    SARG; Specifically androgen-regulated gene protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    6103304..6135100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238976.4 → XP_011237278.1  proline and serine-rich protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011237278.1

    UniProtKB/Swiss-Prot
    Q3V1L9, Q8C5R2, Q8R017, Q8R2Z9
    Conserved Domains (2) summary
    PHA03247
    Location:97 → 261
    PHA03247; large tegument protein UL36; Provisional
    pfam15385
    Location:439 → 469
    SARG; Specifically androgen-regulated gene protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C5R2.3 GenPept UniProtKB/Swiss-Prot:Q8C5R2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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