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sap114 U2 snRNP-associated protein Sap114 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541437, updated on 18-Sep-2024

Summary

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Official Symbol
sap114
Official Full Name
U2 snRNP-associated protein Sap114
Primary source
PomBase:SPAC22A12.09c
Locus tag
SPOM_SPAC22A12.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sap114 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (1172351..1174448, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ER membrane protein O-mannosyltransferase Ogm1 Neighboring gene cardiolipin synthase/ hydrolase fusion protein Crd1;mitochondrial hydrolase, N-terminal portion of Crd1 fusion protein Neighboring gene ncRNA Neighboring gene CDP-alcohol phosphatidyltransferase class-I family protein Neighboring gene dihydroxyacetone kinase Dak1 Neighboring gene exosome subunit Rrp40

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
  2. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
  3. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
  4. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
  5. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
U2 snRNP-associated protein Sap114

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1172351..1174448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018636.3 → NP_593239.1  U2 snRNP-associated protein Sap114 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593239.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13900
    Conserved Domains (3) summary
    smart00648
    Location:42 → 95
    SWAP; Suppressor-of-White-APricot splicing regulator
    pfam11928
    Location:306 → 367
    DUF3446; Domain of unknown function (DUF3446)
    pfam12230
    Location:211 → 441
    PRP21_like_P; Pre-mRNA splicing factor PRP21 like protein
Nucleotide Protein
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