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sec74 guanyl-nucleotide exchange factor Sec74 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542073, updated on 18-Sep-2024

Summary

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Official Symbol
sec74
Official Full Name
guanyl-nucleotide exchange factor Sec74
Primary source
PomBase:SPAC26F1.01
Locus tag
SPOM_SPAC26F1.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPAPJ691.01c
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Genomic context

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See sec74 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5182774..5186159, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pyruvate dehydrogenase e1 component alpha subunit Pda1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative pinin-like protein ppn1 Neighboring gene ncRNA Neighboring gene yippee-like protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains. Chen JS, et al. Yeast, 2016 Sep. PMID 27168121, Free PMC Article
  2. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity ISO
Inferred from Sequence Orthology
more info
  
enables lipid binding ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in exocytosis ISO
Inferred from Sequence Orthology
more info
  
involved_in intracellular protein transport IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
guanyl-nucleotide exchange factor Sec74

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5182774..5186159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020323.3 → NP_594894.2  guanyl-nucleotide exchange factor Sec74 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594894.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10491, Q9URW4, Q9UU74
    Conserved Domains (3) summary
    smart00233
    Location:549 → 676
    PH; Pleckstrin homology domain
    pfam00169
    Location:549 → 676
    PH; PH domain
    pfam01369
    Location:308 → 422
    Sec7; Sec7 domain
Nucleotide Protein
Heading Accession and Version

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