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aar2 U5 snRNP-associated protein Aar2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543611, updated on 18-Sep-2024

Summary

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Official Symbol
aar2
Official Full Name
U5 snRNP-associated protein Aar2
Primary source
PomBase:SPAC3H5.04
Locus tag
SPOM_SPAC3H5.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See aar2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3436000..3438112, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA polymerase alpha catalytic subunit Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene kinesin-14 family minus-end directed microtubule motor Pkl1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Splicing of branchpoint-distant exons is promoted by Cactin, Tls1 and the ubiquitin-fold-activated Sde2. Anil AT, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36095128, Free PMC Article
  2. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
  3. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
  4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spliceosomal tri-snRNP complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U5 snRNP ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
part_of spliceosomal complex NAS
Non-traceable Author Statement
more info
  

General protein information

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Preferred Names
U5 snRNP-associated protein Aar2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3436000..3438112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019612.3 → NP_594188.1  U5 snRNP-associated protein Aar2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594188.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q6LA53
    Conserved Domains (3) summary
    cd13777
    Location:1 → 111
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:148 → 305
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    pfam05282
    Location:14 → 298
    AAR2; AAR2 protein
Nucleotide Protein
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