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Vlet Valette [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32116, updated on 9-Dec-2024

Summary

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Official Symbol
Vletprovided by FlyBase
Official Full Name
Valetteprovided by FlyBase
Primary source
FLYBASE:FBgn0030323
Locus tag
Dmel_CG2371
See related
AllianceGenome:FB:FBgn0030323
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2371; CG2442; CG2443; Dmel\CG2371; Gem8
Summary
Involved in motor behavior. Is expressed in organism. Orthologous to human COMMD10 (COMM domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Vlet in Genome Data Viewer
Location:
10D4-10D4; 1-35 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11677344..11678589, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11571377..11572622, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Methoprene-tolerant Neighboring gene Protein tyrosine phosphatase 10D Neighboring gene bifocal Neighboring gene Phosphorylase kinase gamma Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of Survival Motor Neuron in Glia Impacts Survival but has no Effect on Neuromuscular Function in Drosophila. Farrugia M, et al. Neuroscience, 2022 May 21. PMID 35314252
  2. Novel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation. Lanfranco M, et al. FEBS Lett, 2017 Nov. PMID 28949413
  3. Composition of the Survival Motor Neuron (SMN) Complex in Drosophila melanogaster. Matera AG, et al. G3 (Bethesda), 2019 Feb 7. PMID 30563832, Free PMC Article
  4. MicroRNA-Dependent Control of Sensory Neuron Function Regulates Posture Behavior in Drosophila. Klann M, et al. J Neurosci, 2021 Oct 6. PMID 34417328, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in motor behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
valette
Names
CG2371-PA
CG2371-PB
CG2371-PC
Gemin8
Vlet-PA
Vlet-PB
Vlet-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11677344..11678589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167294.2 → NP_727546.1  valette, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727546.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHT4
    Related
    FBpp0073379
    Conserved Domains (1) summary
    cl06336
    Location:24 → 187
    Commd; COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene MURR1 product, and related proteins. Presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in ...

  2. NM_167293.1 → NP_727545.1  valette, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727545.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHT4
    Related
    FBpp0073377, FBtr0073532
    Conserved Domains (1) summary
    cl06336
    Location:24 → 187
    Commd; COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene MURR1 product, and related proteins. Presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in ...

  3. NM_132510.3 → NP_572738.1  valette, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572738.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VYV9, Q9VYW0
    Related
    FBpp0073378
    Conserved Domains (1) summary
    cd04758
    Location:12 → 224
    Commd10; COMM_Domain containing protein 10. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0KHT4 Q0KHT4
Q9VYV9 Q9VYV9

Gene LinkOut

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