U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tsp42Eq Tetraspanin 42Eq [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35628, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Tsp42Eqprovided by FlyBase
Official Full Name
Tetraspanin 42Eqprovided by FlyBase
Primary source
FLYBASE:FBgn0033138
Locus tag
Dmel_CG12832
See related
AllianceGenome:FB:FBgn0033138
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12832; Dm.Tsp42Eq; Dmel\CG12832
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tsp42Eq in Genome Data Viewer
Location:
42E7-42E7; 2-55 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7062108..7063569, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2949613..2951074, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Tetraspanin 42Ep Neighboring gene Tetraspanin 42Eo Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 3 Neighboring gene Tetraspanin 42Er Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A mucin-type O-glycosyltransferase modulates cell adhesion during Drosophila development. Zhang L, et al. J Biol Chem, 2008 Dec 5. PMID 18835818, Free PMC Article
  2. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
  3. Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma. Jeibmann A, et al. J Neurooncol, 2015 Sep. PMID 26224160
  4. Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Fradkin LG, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370414, Free PMC Article
  5. The tetraspanin superfamily in insects. Todres E, et al. Insect Mol Biol, 2000 Dec. PMID 11122467

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tetraspanin 42Eq
Names
CG12832-PA
Tsp42Eq-PA
tetraspanin 42E

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7062108..7063569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078919.3 → NP_523643.2  tetraspanin 42Eq [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523643.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6U8
    Related
    FBpp0088129
    Conserved Domains (2) summary
    cd03127
    Location:95 → 173
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:8 → 209
    Tetraspannin; Tetraspanin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z6U8 A1Z6U8
Q8SZ98 Q8SZ98

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools