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set-24 SPK domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3565594, updated on 4-Jan-2025

Summary

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Official Symbol
set-24
Official Full Name
SPK domain-containing protein
Primary source
WormBase:WBGene00012845
Locus tag
CELE_Y43F11A.5
See related
AllianceGenome:WB:WBGene00012845
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in germ line. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See set-24 in Genome Data Viewer
Location:
chromosome: II
Exon count:
13
Sequence:
Chromosome: II; NC_003280.10 (12114971..12130968, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural Genetic Variation in a Multigenerational Phenotype in C. elegans. Frézal L, et al. Curr Biol, 2018 Aug 20. PMID 30078564, Free PMC Article
  2. Genome-wide association and environmental suppression of the mortal germline phenotype of wild C. elegans. Frézal L, et al. EMBO Rep, 2023 Dec 6. PMID 37983674, Free PMC Article
  3. Functional importance of an inverted formin C-terminal tail at morphologically dynamic epithelial junctions. Hegsted A, et al. Cytoskeleton (Hoboken), 2019 Apr. PMID 31215743, Free PMC Article
  4. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
  5. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
SPK domain-containing protein
NP_496579.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    12114971..12130968 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064178.7 → NP_496579.3  SPK domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496579.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2G8
    Conserved Domains (3) summary
    smart00317
    Location:58 → 162
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00583
    Location:243 → 354
    SPK; domain in SET and PHD domain containing proteins and protein kinases
    pfam04435
    Location:529 → 632
    SPK; Domain of unknown function (DUF545)
Nucleotide Protein
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